References
Query Results -- Details
MGI Accession ID: MGI:58664
J Number: J:10209
Other Accession IDs:
Title: A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse.
Authors: Moser AR; Pitot HC; Dove WF
Journal: Science
Volume: 247
Issue: 4940
Date: 1990 Jan 19
Year: 1990
Pages: 322-4
Review Status: Peer Reviewed
Abstract:
In a pedigree derived from a mouse treated with the mutagen ethylnitrosourea, a mutation has been identified that predisposes to spontaneous intestinal cancer. The mutant gene was found to be dominantly expressed and fully penetrant. Affected mice developed multiple adenomas throughout the entire intestinal tract at an early age.
Additional Information:
