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Gene Expression Data
Query Results -- Details

Reference: J:109486 Vernersson E, Gene Expr Patterns 2006 Jun;6(5):448-61
Assay type: RNA in situ
MGI Accession ID: MGI:3640085
Gene symbol: Alk
Gene name: anaplastic lymphoma kinase
Modification date: 03/27/2013
Probe: Alk cDNA2
Probe preparation: Antisense RNA labelled with digoxigenin
Visualized with: Alkaline phosphatase
Specimens Used
Table 1, E10.5 Table 1, E11.5 Table 1, E12.5 Table 1, E13.5 Table 1, E14.5 Table 1, E16.5 1a 1b 1c 1d 1e 1f 2a 2b 2c 2d 2e 2f 3a 3b 3c 3d 3e 3f 3g not shown not shown not shown not shown not shown not shown S1a S1b S1c S1d S1e S1f S1g S1h S1i
Genetic Background C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6 C57BL/6
Mutant Allele(s)                                                                                
Age E 10.5 (a)E 11.5 (a)E 12.5 (a)E 13.5 (a)E 14.5 (a)E 16.5 (a)E 11.5 (a)E 12.5 (a)E 12.5 (a)E 14.5 (a)E 10.5 (a)E 12.5 (a)E 12.5 (a)E 13.5 (a)E 11.5 (a)E 12.5 (a)E 14.5 (a)E 13.5 (a)E 11.5 (a)E 12.5 (a)E 13.5 (a)E 12.5 (a)E 12.5 (a)E 13.5 (a)E 14.5 (a)E 10.5 (a)E 11.5 (a)E 13.5 (a)E 14.5 (a)E 15.5 (a)E 16.5 (a)E 16.5 (a)E 12.5 (a)E 10.5 (a)E 13.5 (a)E 14.5 (a)E 12.5 (a)E 13.5 (a)E 14.5 (a)E 14.5 (a)
Sex Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified Not Specified
Type section section section section section section section section section section section section section section section section section section section section section section section section section section section section section section section section section section section section section section section section
Fixation 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde 4% Paraformaldehyde
Embedding Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection Cryosection
Notes:
(a) Age of embryo at noon of plug day not specified in reference.

Results: Table 1, E10.5 (embryonic day 10.5; C57BL/6)
Structure Level Pattern Note Image
TS17: diencephalon Present Not Specified    
TS17: facial VII ganglion Present Not Specified    
TS17: 4th ventricle Present Regionally restricted (a)  
Notes:
(a) Expression is in the ventral part.

Results: Table 1, E11.5 (embryonic day 11.5; C57BL/6)
Structure Level Pattern Note Image
TS19: 2nd branchial arch Present Not Specified    
TS19: diencephalon Present Not Specified    
TS19: facial VII ganglion Present Not Specified    
TS19: vagus X inferior ganglion Present Not Specified    
TS19: oesophagus Present Not Specified    
TS19: stomach Present Not Specified    
TS19: 4th ventricle Present Regionally restricted (a)  
TS19: future spinal cord Present Regionally restricted (b)  
TS19: nasal epithelium Present Regionally restricted (c)  
TS19: head mesenchyme Present Regionally restricted (d)  
Notes:
(a) Expression is in the ventral part.
(b) Expression is ventral.
(c) Expression is in the ventral part of the olfactory epithelium.
(d) Expression is in the area between the nasal pit and lateral ventricle.

Results: Table 1, E12.5 (embryonic day 12.5; C57BL/6)
Structure Level Pattern Note Image
TS20: dorsal aorta Present Not Specified    
TS20: vibrissa Present Not Specified    
TS20: diencephalon Present Not Specified    
TS20: cerebral cortex subventricular zone Present Not Specified    
TS20: cerebral cortex ventricular layer Present Not Specified    
TS20: medulla oblongata Present Not Specified    
TS20: pons Present Not Specified    
TS20: midbrain roof plate Present Not Specified    
TS20: facial VII ganglion Present Not Specified    
TS20: vagus X inferior ganglion Present Not Specified    
TS20: vestibulocochlear VIII ganglion Present Not Specified    
TS20: spinal cord Present Not Specified    
TS20: sympathetic nervous system Present Not Specified    
TS20: endolymphatic sac Present Not Specified    
TS20: posterior semicircular canal Present Not Specified    
TS20: vomeronasal organ Present Not Specified    
TS20: oesophagus Present Not Specified    
TS20: tongue Present Not Specified    
TS20: stomach Present Not Specified    
TS20: midgut Present Not Specified    
TS20: 4th ventricle Present Regionally restricted (a)  
TS20: midbrain Present Regionally restricted (b)  
TS20: utricle Present Regionally restricted (c)  
TS20: optic chiasma Present Regionally restricted (d)  
TS20: olfactory epithelium Present Regionally restricted (e)  
TS20: head mesenchyme Present Regionally restricted (f)  
TS20: embryo mesenchyme Present Regionally restricted (g)  
TS20: extraembryonic component Present Regionally restricted (h)  
TS20: forelimb Present Regionally restricted (i)  
TS20: hindlimb Present Regionally restricted (i)  
Notes:
(a) Expression is in the ventral part.
(b) Expression is in the tegmentum.
(c) Expression is in the lateral semicircular canal.
(d) Expression is in the dorsal epithelium in the region of the optic chiasm.
(e) Expression is in the ventral part of the olfactory epithelium.
(f) Expression is in the area between the nasal pit and lateral ventricle and outside the most posterior part of the nasal cavity.
(g) Expression is in the premuscle mesodermal condensations.
(h) Expression is in the umbilical cord.
(i) Elongated stain in the limbs.

Results: Table 1, E13.5 (embryonic day 13.5; C57BL/6)
Structure Level Pattern Note Image
TS21: dorsal aorta Present Not Specified    
TS21: diencephalon Present Not Specified    
TS21: cerebral cortex subventricular zone Present Not Specified    
TS21: cerebral cortex ventricular layer Present Not Specified    
TS21: medulla oblongata Present Not Specified    
TS21: pons Present Not Specified    
TS21: midbrain roof plate Present Not Specified    
TS21: facial VII ganglion Present Not Specified    
TS21: vagus X inferior ganglion Present Not Specified    
TS21: vestibulocochlear VIII ganglion Present Not Specified    
TS21: spinal cord Present Not Specified    
TS21: sympathetic ganglion Present Not Specified    
TS21: endolymphatic sac Present Not Specified    
TS21: lateral semicircular canal Present Not Specified    
TS21: posterior semicircular canal Present Not Specified    
TS21: vomeronasal organ Present Not Specified    
TS21: oesophagus Present Not Specified    
TS21: tongue Present Not Specified    
TS21: stomach Present Not Specified    
TS21: midgut Present Not Specified    
TS21: 4th ventricle Present Regionally restricted (a)  
TS21: midbrain Present Regionally restricted (b)  
TS21: trigeminal V nerve Present Regionally restricted (c)  
TS21: autonomic nervous system Present Regionally restricted (d)  
TS21: olfactory epithelium Present Regionally restricted (e)  
TS21: head mesenchyme Present Regionally restricted (f)  
TS21: skeletal muscle Present Regionally restricted (g)  
TS21: forelimb Present Regionally restricted (h)  
TS21: hindlimb Present Regionally restricted (h)  
Notes:
(a) Expression is in the ventral part.
(b) Expression is in the tegmentum.
(c) Expression is in the maxillary division of the trigeminal (V) nerve.
(d) Expression is in the ciliary ganglion.
(e) Expression is in the ventral part of the olfactory epithelium.
(f) Expression is outside the most posterior part of the nasal cavity.
(g) Expression is in the long muscle of the neck.
(h) Elongated stain in the limbs.

Results: Table 1, E14.5 (embryonic day 14.5; C57BL/6)
Structure Level Pattern Note Image
TS22: dorsal aorta Present Not Specified    
TS22: diencephalon Present Not Specified    
TS22: cerebral cortex subventricular zone Present Not Specified    
TS22: cerebral cortex ventricular layer Present Not Specified    
TS22: medulla oblongata Present Not Specified    
TS22: pons Present Not Specified    
TS22: midbrain roof plate Present Not Specified    
TS22: midbrain tegmentum Present Not Specified    
TS22: vagus X inferior ganglion Present Not Specified    
TS22: vestibulocochlear VIII ganglion Present Not Specified    
TS22: spinal cord Present Not Specified    
TS22: sympathetic ganglion Present Not Specified    
TS22: neural retina epithelium Present Not Specified    
TS22: vomeronasal organ Present Not Specified    
TS22: oesophagus Present Not Specified    
TS22: tongue Present Not Specified    
TS22: stomach Present Not Specified    
TS22: midgut Present Not Specified    
TS22: trigeminal V nerve Present Regionally restricted (a)  
TS22: olfactory epithelium Present Regionally restricted (b)  
TS22: skeletal muscle Present Regionally restricted (c)  
TS22: forelimb Present Regionally restricted (d)  
TS22: hindlimb Present Regionally restricted (d)  
Notes:
(a) Expression is in the maxillary division of the trigeminal (V) nerve.
(b) Expression is in the ventral part of the olfactory epithelium.
(c) Expression is in the long muscle of the neck.
(d) Elongated stain in the limbs.

Results: Table 1, E16.5 (embryonic day 16.5; C57BL/6)
Structure Level Pattern Note Image
TS24: diencephalon Present Not Specified    
TS24: cerebral cortex subventricular zone Present Not Specified    
TS24: vestibulocochlear VIII ganglion Present Not Specified    
TS24: dorsal root ganglion Present Not Specified    
TS24: sublingual gland Present Not Specified    
TS24: submandibular gland Present Not Specified    
TS24: trigeminal V nerve Present Regionally restricted (a)  
TS24: sympathetic ganglion Present Regionally restricted (b)  
Notes:
(a) Expression is in the rootlets and the ophthalmic division of the trigeminal (V) nerve.
(b) Expression is in the lumbar sympathetic ganglion.

Results: 1a (embryonic day 11.5; C57BL/6)
Structure Level Pattern Note Image images
TS19: diencephalon lateral wall Present Regionally restricted (a) Figure 1a
Notes:
(a) Expression is in the wall of diencephalon at the level of infundibular recess.

Results: 1b (embryonic day 12.5; C57BL/6)
Structure Level Pattern Note Image images
TS20: diencephalon Present Regionally restricted (a) Figure 1b
Notes:
(a) Expression is in a specific cell population.

Results: 1c (embryonic day 12.5; C57BL/6)
Structure Level Pattern Note Image images
TS20: telencephalon Present Regionally restricted (a) Figure 1c
Notes:
(a) Expression is in the dorsal part of the lateral ventricle wall, this area presumably corresponds to part of the amygdala.

Results: 1d (embryonic day 14.5; C57BL/6)
Structure Level Pattern Note Image images
TS22: telencephalon ventricular layer Present Not Specified   Figure 1d
TS22: telencephalon Present Regionally restricted (a) Figure 1d
TS22: cortical plate Absent     Figure 1d
TS22: telencephalon marginal layer Absent     Figure 1d
Notes:
(a) Expression is in the subventricular zone and is absent in the intermediate zone.

Results: 1e (embryonic day 10.5; C57BL/6)
Structure Level Pattern Note Image images
TS17: hindbrain lateral wall Present Regionally restricted (a) Figure 1e
Notes:
(a) Expression is in the ventral part.

Results: 1f (embryonic day 12.5; C57BL/6)
Structure Level Pattern Image images
TS20: midbrain roof plate Present Not Specified Figure 1f
TS20: midbrain Present Not Specified Figure 1f

Results: 2a (embryonic day 12.5; C57BL/6)
Structure Level Pattern Note Image images
TS20: posterior semicircular canal Present Not Specified   Figure 2a
TS20: utricle Present Regionally restricted (a) Figure 2a
Notes:
(a) Expression is in the lateral semicircular canal.

Results: 2b (embryonic day 13.5; C57BL/6)
Structure Level Pattern Image images
TS21: vestibulocochlear VIII ganglion Present Not Specified Figure 2b
TS21: endolymphatic sac Present Not Specified Figure 2b

Results: 2c (embryonic day 11.5; C57BL/6)
Structure Level Pattern Image images
TS19: facial VII ganglion Present Not Specified Figure 2c

Results: 2d (embryonic day 12.5; C57BL/6)
Structure Level Pattern Note Image images
TS20: oesophagus mesenchyme Strong Regionally restricted (a) Figure 2d
TS20: stomach mesenchyme Strong Regionally restricted (a) Figure 2d
TS20: duodenum caudal part mesenchyme Strong Regionally restricted (a) Figure 2d
Notes:
(a) Expression is surrounding the esophagus, stomach and midgut (duodenum).

Results: 2e (embryonic day 14.5; C57BL/6)
Structure Level Pattern Image images
TS22: neural retina epithelium Present Not Specified Figure 2e

Results: 2f (embryonic day 13.5; C57BL/6)
Structure Level Pattern Note Image images
TS21: autonomic nervous system Present Regionally restricted (a) Figure 2f
Notes:
(a) Expression is in the ciliary ganglion.

Results: 3a (embryonic day 11.5; C57BL/6)
Structure Level Pattern Image images
TS19: neural tube marginal layer Present Not Specified Figure 3a

Results: 3b (embryonic day 12.5; C57BL/6)
Structure Level Pattern Image images
TS20: sympathetic nervous system Present Not Specified Figure 3b

Results: 3c (embryonic day 13.5; C57BL/6)
Structure Level Pattern Note Image images
TS21: spinal cord Present Regionally restricted (a) Figure 3c
TS21: tail spinal cord Present Regionally restricted (a) Figure 3c
Notes:
(a) Expression in the spinal cord switches from a ventral stain rostrally to a dorsal stain caudally.

Results: 3d (embryonic day 12.5; C57BL/6)
Structure Level Pattern Image images
TS20: olfactory epithelium Present Not Specified Figure 3d
TS20: vomeronasal organ Present Not Specified Figure 3d

Results: 3e (embryonic day 12.5; C57BL/6)
Structure Level Pattern Note Image images
TS20: head mesenchyme Present Regionally restricted (a) Figure 3e
Notes:
(a) Expression is ventral to the nasal cavity and posterior to the lateral ventricle of the brain.

Results: 3f (embryonic day 13.5; C57BL/6)
Structure Level Pattern Note Image images
TS21: nose Present Regionally restricted (a) Figure 3f
Notes:
(a) Expression is dorsal to the nasal epithelium.

Results: 3g (embryonic day 14.5; C57BL/6)
Structure Level Pattern Note Image images
TS22: tongue Present Regionally restricted (a) Figure 3g
Notes:
(a) Expression is below the intrinsic muscle component of the tongue.

Results: not shown (embryonic day 10.5; C57BL/6)
Structure Level Pattern Note Image
TS17: diencephalon Present Regionally restricted (a)  
TS17: midbrain Absent      
Notes:
(a) Expression is in the neuroepithelium surrounding the infundibular recess of diencephalon.

Results: not shown (embryonic day 11.5; C57BL/6)
Structure Level Pattern Note Image
TS19: 4th ventricle Present Regionally restricted (a)  
TS19: midbrain Absent      
Notes:
(a) Expression is in the ventral part.

Results: not shown (embryonic day 13.5; C57BL/6)
Structure Level Pattern Image
TS21: midbrain Present Not Specified  
TS21: midbrain roof plate Present Not Specified  

Results: not shown (embryonic day 14.5; C57BL/6)
Structure Level Pattern Image
TS22: midbrain Present Not Specified  
TS22: midbrain roof plate Present Not Specified  

Results: not shown (embryonic day 15.5; C57BL/6)
Structure Level Pattern Image
TS23: cerebral cortex subventricular zone Absent    
TS23: cerebral cortex ventricular layer Absent    

Results: not shown (embryonic day 16.5; C57BL/6)
Structure Level Pattern Image
TS24: cerebral cortex ventricular layer Absent    
TS24: midbrain Absent    

Results: S1a (embryonic day 16.5; C57BL/6)
Structure Level Pattern Image images
TS24: diencephalon Weak Not Specified Figure S1a

Results: S1b (embryonic day 12.5; C57BL/6)
Structure Level Pattern Note Image images
TS20: optic chiasma Present Regionally restricted (a) Figure S1b
Notes:
(a) Expression is in the dorsal epithelium.

Results: S1c (embryonic day 10.5; C57BL/6)
Structure Level Pattern Image images
TS17: facial VII ganglion Present Not Specified Figure S1c

Results: S1d (embryonic day 13.5; C57BL/6)
Structure Level Pattern Image images
TS21: facial VII ganglion Present Not Specified Figure S1d
TS21: vestibulocochlear VIII ganglion Present Not Specified Figure S1d

Results: S1e (embryonic day 14.5; C57BL/6)
Structure Level Pattern Image images
TS22: midgut loop Present Not Specified Figure S1e

Results: S1f (embryonic day 12.5; C57BL/6)
Structure Level Pattern Image images
TS20: vibrissa Present Not Specified Figure S1f

Results: S1g (embryonic day 13.5; C57BL/6)
Structure Level Pattern Note Image images
TS21: skeletal muscle Present Regionally restricted (a) Figure S1g
Notes:
(a) Expression is in the area covering the long muscles of neck.

Results: S1h (embryonic day 14.5; C57BL/6)
Structure Level Pattern Note Image images
TS22: hindlimb Present Regionally restricted (a) Figure S1h
Notes:
(a) Expression is like a protrusion in the limb.

Results: S1i (embryonic day 14.5; C57BL/6)
Structure Level Pattern Image images
TS22: dorsal aorta Strong Not Specified Figure S1i

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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory