MGI_4.32 - Phenotypic Alleles Query Results (Summary)

Phenotypic Alleles
Query Results -- Summary
Symbol
Name
ID
Lrp2
low density lipoprotein receptor-related protein 2
MGI:95794
25 matching Alleles (1 Gene/Marker represented)
                                                             Allele Symbol
Name                                                               Chr      Synonyms                  Category                                                                                                                                                       Phenotypic Classes                                                                                                                                                               Human Diseases                                                                                                                                                                                    Allelic Composition
(Genetic Background)                                                                                                                                                                

Lrp2^m267Asp
low density lipoprotein receptor-related protein 2; mutation 267, Andrew S Peterson                                               2    megalin^line267    Chemically induced (ENU)         ['nervous system']                                                                                                                                                                                                                                                                                      ['']                                                 ['Lrp2^m267Asp/Lrp2^m267Asp
Tg(mI56i-lacZ)1Mekk/0


Allele Symbol
Gene; Allele Name
Chr
Synonyms
Category
Observed Phenotypes in Mouse
Allelic Composition
(Genetic Background)


Affected Anatomical Systems
Similar Human Diseases

']                                                                                                                                                                                                                                                                         

Lrp2^tm1Her
low density lipoprotein receptor-related protein 2; targeted mutation 1, Joachim Herz                                              2    Meg KO, megalin-  Targeted (knock-out)             ['reproductive, homeostasis, endocrine/exocrine', 'lethality/prenatal-perinatal, growth/size, embryogenesis, nervous system, respiratory, homeostasis, craniofacial, renal/urinary, skeleton, vision/eye, cellular', 'lethality/prenatal-perinatal, hearing/vestibular/ear', 'hearing/vestibular/ear']  ['', 'Fanconi Renotubular Syndrome 134600', '', '']  ['Lrp2^tm1Her/Lrp2^tm1Her
    (either: (involves: 129S7/SvEvBrd * CD-1) or (involves: 129/SvEmcTer * 129S7/SvEvBrd * C57BL/6N))
', 'Lrp2^tm1Her/Lrp2^tm1Her
    (involves: 129S7/SvEvBrd)
', 'Lrp2^tm1Her/Lrp2^tm1Her
    (involves: 129S7/SvEvBrd * C57BL/6)
', 'Lrp2^tm1Her/Lrp2⁺
    (involves: 129S7/SvEvBrd * C57BL/6)']

Lrp2^tm1Tew
low density lipoprotein receptor-related protein 2; targeted mutation 1, Thomas E Willnow                                          2    megalin^lox        Targeted (Floxed/Frt)            ['skeleton', 'homeostasis, skeleton, renal/urinary']                                                                                                                                                                                                                                                    ['', '']                                             ['Lrp2^tm1Tew/Lrp2^tm1Tew
    (Not Specified)
', 'Lrp2^tm1Tew/Lrp2^tm1Tew
Tg(APOE-cre)VITew/0
    (Not Specified)
conditionally targeted']                                                                                                                                                                                                          

Lrp2^{Gt(CMHD-GT_501A1-3)Cmhd}
low density lipoprotein receptor-related protein 2; gene trap CMHD-GT_501A1-3, Centre for Modeling Human Disease  2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(E323E01)Wrst}
low density lipoprotein receptor-related protein 2; gene trap E323E01, German Gene Trap Consortium                        2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(E323G02)Wrst}
low density lipoprotein receptor-related protein 2; gene trap E323G02, German Gene Trap Consortium                        2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(E324C09)Wrst}
low density lipoprotein receptor-related protein 2; gene trap E324C09, German Gene Trap Consortium                        2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(EUCG0001c04)Hmgu}
low density lipoprotein receptor-related protein 2; gene trap EUCG0001c04, Helmholtz Zentrum Muenchen GmbH            2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(EUCG0001c11)Hmgu}
low density lipoprotein receptor-related protein 2; gene trap EUCG0001c11, Helmholtz Zentrum Muenchen GmbH            2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(EUCG0001f01)Hmgu}
low density lipoprotein receptor-related protein 2; gene trap EUCG0001f01, Helmholtz Zentrum Muenchen GmbH            2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(EUCG0002c07)Hmgu}
low density lipoprotein receptor-related protein 2; gene trap EUCG0002c07, Helmholtz Zentrum Muenchen GmbH            2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(EUCG0003c06)Hmgu}
low density lipoprotein receptor-related protein 2; gene trap EUCG0003c06, Helmholtz Zentrum Muenchen GmbH            2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(EUCG0003e10)Hmgu}
low density lipoprotein receptor-related protein 2; gene trap EUCG0003e10, Helmholtz Zentrum Muenchen GmbH            2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(EUCG0005c04)Hmgu}
low density lipoprotein receptor-related protein 2; gene trap EUCG0005c04, Helmholtz Zentrum Muenchen GmbH            2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(EUCG0007e08)Hmgu}
low density lipoprotein receptor-related protein 2; gene trap EUCG0007e08, Helmholtz Zentrum Muenchen GmbH            2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^Gt(Ex184)Byg
low density lipoprotein receptor-related protein 2; gene trap Ex184, BayGenomics                                             2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(G030C09)Wrst}
low density lipoprotein receptor-related protein 2; gene trap G030C09, German Gene Trap Consortium                        2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(G032E05)Wrst}
low density lipoprotein receptor-related protein 2; gene trap G032E05, German Gene Trap Consortium                        2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(KST224)Byg}
low density lipoprotein receptor-related protein 2; gene trap KST224, BayGenomics                                           2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(LST091)Byg}
low density lipoprotein receptor-related protein 2; gene trap LST091, BayGenomics                                           2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(OST245950)Lex}
low density lipoprotein receptor-related protein 2; gene trap OST245950, Lexicon Genetics                                2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(OST284920)Lex}
low density lipoprotein receptor-related protein 2; gene trap OST284920, Lexicon Genetics                                2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(OST32858)Lex}
low density lipoprotein receptor-related protein 2; gene trap OST32858, Lexicon Genetics                                  2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{Gt(OST359359)Lex}
low density lipoprotein receptor-related protein 2; gene trap OST359359, Lexicon Genetics                                2                      Gene trapped
(Cell Line)          []                                                                                                                                                                                                                                                                                                      []                                                   []                                                                                                                                                                                                                                                                                                                                                                     

Lrp2^{tm1(KOMP)Vlcg}
low density lipoprotein receptor-related protein 2; targeted mutation 1, Velocigene                                         2                      Targeted (knock-out)
(Cell Line)  []                                                                                                                                                                                                                                                                                                      []                                                   []
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