Symbol Name ID

Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) MGI:2135607

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2 matching Alleles (1 Gene/Marker represented)

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                                                           Allele Symbol
Name                                                             Chr                  Synonyms                        Category                                                                                                                                      Phenotypic Classes                                                                                                                                                           Human Diseases                            

Sirt1tm1.2Cxd
sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae); targeted mutation 1.2,  Chu-Xia Deng    10   Sirt1flox5-6                             Targeted (Floxed/Frt)  homeostasis, liver/biliary                                                                                                                                                                                                                                                     Fatty Liver Disease, Nonalcoholic, Susceptibility to, 1; NAFLD1 613282

Sirt1tm1Mcby
sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae); targeted mutation 1, Michael W McBurney  10   Sir2-, sir2alpha null, SIRT1-, Sirt1 KO  Targeted (knock-out)   adipose, behavior, cardiovascular, cellular, craniofacial, digestive/alimentary, embryogenesis, endocrine/exocrine, growth/size, hematopoietic, homeostasis, immune, limbs/digits/tail, mortality/aging, nervous system, renal/urinary, reproductive, respiratory, vision/eye  Diabetes Insipidus, Nephrogenic, Autosomal 125800