Symbol Name ID

Psen1 presenilin 1 MGI:1202717

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10 matching Alleles (1 Gene/Marker represented)

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                       Allele Symbol
Name                         Chr                    Synonyms                          Category                                                                            Phenotypic Classes                                                                                          Human Diseases                     

Psen1tm1Bdes
presenilin 1; targeted mutation 1, Bart de Strooper
  12   PS1-                                         Targeted (knock-out)   cardiovascular, cellular, craniofacial, growth/size, limbs/digits/tail, mortality/aging, nervous system, skeleton                                          Alzheimer Disease; AD 104300                            

Psen1tm1Dgf
presenilin 1; targeted mutation 1, Dorothy G Flood    12   PS-1P264L, Psen1tm1Rsim                      Targeted (knock-in)    no abnormal phenotype observed                                                                                                                                                                                     

Psen1tm1Jzt
presenilin 1; targeted mutation 1, Joe Z Tsien        12   PS1 (f)                                      Targeted (Floxed/Frt)  behavior, cellular, growth/size, nervous system                                                                                                            Alzheimer Disease 4 606889; Alzheimer Disease; AD 104300

Psen1tm1Lpr
presenilin 1; targeted mutation 1, Laurent Pradier    12   PS1KI, Ps1M233T,L235P                        Targeted (knock-in)    homeostasis                                                                                                                                                                                                        

Psen1tm1Mpm
presenilin 1; targeted mutation 1, Mark P Mattson     12   PS1KI, PS1M146V, PS-1 M146V KI, PS1M146VKI-  Targeted (knock-in)    behavior, cardiovascular, cellular, growth/size, homeostasis, limbs/digits/tail, mortality/aging, nervous system                                           Alzheimer Disease 3 607822; Alzheimer Disease; AD 104300

Psen1tm1Pcw
presenilin 1; targeted mutation 1, Philip C Wong      12   PS1-                                         Targeted (knock-out)   behavior, cardiovascular, cellular, craniofacial, embryogenesis, growth/size, limbs/digits/tail, mortality/aging, nervous system, skeleton                 Alzheimer Disease 3 607822; Alzheimer Disease; AD 104300

Psen1tm1Shn
presenilin 1; targeted mutation 1, Jie Shen           12   PS1-                                         Targeted (knock-out)   cardiovascular, cellular, craniofacial, embryogenesis, growth/size, integument, limbs/digits/tail, mortality/aging, nervous system, respiratory, skeleton  Alzheimer Disease 3 607822; Alzheimer Disease; AD 104300

Psen1tm1Tak
presenilin 1; targeted mutation 1, Junji Takeda       12   mPS1, PS1 I213T, PS1/I213T                   Targeted (knock-in)    behavior                                                                                                                                                   Alzheimer Disease; AD 104300                            

Psen1tm1Vln
presenilin 1; targeted mutation 1, Fred Van Leuven    12   PS1-flox                                     Targeted (Floxed/Frt)  behavior, nervous system, other                                                                                                                            Alzheimer Disease 3 607822; Alzheimer Disease; AD 104300

Psen1tm1Zhe
presenilin 1; targeted mutation 1, Hui Zheng          12   PS1 deltaE10                                 Targeted (knock-out)