Symbol Name ID

Mecp2 methyl CpG binding protein 2 MGI:99918

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21 matching Alleles (1 Gene/Marker represented)

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                                            Allele Symbol
Name                                              Chr                       Synonyms                                  Category                                                                                                Phenotypic Classes                                                                                         Human Diseases     

Mecp2tm1.1Bird
methyl CpG binding protein 2; targeted mutation 1.1, Adrian Bird                             X    Mecp2-, MeCP2Bird, Mecp2tm1-1Bird, Mecp2tm1+1Bird  Targeted (knock-out)              adipose, behavior, cellular, craniofacial, endocrine/exocrine, growth/size, hearing/vestibular/ear, homeostasis, mortality/aging, nervous system, reproductive, respiratory, skeleton  Rett Syndrome; RTT 312750

Mecp2tm1.1Irsf
methyl CpG binding protein 2; targeted mutation 1.1, International Rett Syndrome Foundation  X    Mecp2*R255X                                        Targeted (knock-in)               behavior, growth/size                                                                                                                                                                                           

Mecp2tm1.1Jae
methyl CpG binding protein 2; targeted mutation 1.1, Rudolf Jaenisch                          X    Mecp1lox, Mecp2tm1-1Jae                            Targeted (knock-out)              behavior, growth/size, homeostasis, mortality/aging, nervous system, respiratory                                                                                                       Rett Syndrome; RTT 312750

Mecp2tm1.1Joez
methyl CpG binding protein 2; targeted mutation 1.1, Zhaolan Zhou                            X    Mecp2T158A, MeCP2 T158A                            Targeted (knock-in)               behavior, growth/size, mortality/aging, nervous system                                                                                                                                 Rett Syndrome; RTT 312750

Mecp2tm1.1Meg
methyl CpG binding protein 2; targeted mutation 1.1, Michael E Greenberg                      X    MeCP2 S421A                                        Targeted (knock-in)               behavior, nervous system                                                                                                                                                                                        

Mecp2tm1.1Mitoh
methyl CpG binding protein 2; targeted mutation 1.1, Masayuki Itoh                          X    Xe2-                                               Targeted (other)                  cellular, embryogenesis, mortality/aging                                                                                                                                                                        

Mecp2tm1.1Vnar
methyl CpG binding protein 2; targeted mutation 1.1, Vinodh Narayanan                        X    Mecp2*a140v, Naidu1                                Targeted (knock-in)               nervous system, reproductive                                                                                                                                                                                    

Mecp2tm1Bird
methyl CpG binding protein 2; targeted mutation 1, Adrian Bird                                 X    Mecp2lox                                           Targeted (Floxed/Frt)             behavior, craniofacial, endocrine/exocrine, growth/size, integument, mortality/aging, nervous system, reproductive, respiratory                                                        Rett Syndrome; RTT 312750

Mecp2tm1Csb
methyl CpG binding protein 2; targeted mutation 1, Cecile Spielewoy Blaustein                   X    MeCP2-EGFP                                         Targeted (Reporter)                                                                                                                                                                                                                               

Mecp2tm1Hzo
methyl CpG binding protein 2; targeted mutation 1, Huda Zoghbi                                  X    Mecp2308                                           Targeted (knock-out)              behavior, cellular, integument, mortality/aging, nervous system, skeleton                                                                                                              Rett Syndrome; RTT 312750

Mecp2tm1Jae
methyl CpG binding protein 2; targeted mutation 1, Rudolf Jaenisch                              X    Mecp2lox                                           Targeted (Floxed/Frt)             behavior, growth/size, mortality/aging, nervous system, respiratory                                                                                                                    Rett Syndrome; RTT 312750

Mecp2tm1Jchr
methyl CpG binding protein 2; targeted mutation 1, John Christodoulou                          X                                                       Targeted (knock-out)              behavior, mortality/aging                                                                                                                                                                                       

Mecp2tm1Pplt
methyl CpG binding protein 2; targeted mutation 1, Patrick P L Tam                             X    Mecp2tm1neoTam                                     Targeted (knock-out)              behavior, craniofacial, growth/size, integument, mortality/aging, nervous system, respiratory, skeleton                                                                                                         

Mecp2tm1Vnar
methyl CpG binding protein 2; targeted mutation 1, Vinodh Narayanan
                            X    Mecp2*a140v                                        Targeted (knock-in)               nervous system, reproductive                                                                                                                                                           Rett Syndrome; RTT 312750

Mecp2tm2.1Jae
methyl CpG binding protein 2; targeted mutation 2.1, Rudolf Jaenisch                          X    Mecp2S80A                                          Targeted (knock-in)               behavior, growth/size                                                                                                                                                                                           

Mecp2tm2.1Joez
methyl CpG binding protein 2; targeted mutation 2.1, Zhaolan Zhou                            X    Mecp2loxP                                          Targeted (knock-in)               no abnormal phenotype observed                                                                                                                                                                                  

Mecp2tm2Bird
methyl CpG binding protein 2; targeted mutation 2, Adrian Bird                                 X    Mecp2lox-stop, Mecp2stop                           Targeted (Floxed/Frt)             behavior, growth/size, mortality/aging, nervous system, respiratory                                                                                                                    Rett Syndrome; RTT 312750

Mecp2tm2Jae
methyl CpG binding protein 2; targeted mutation 2, Rudolf Jaenisch                              X    LSL-Mecp2S80A                                      Targeted (Floxed/Frt)                                                                                                                                                                                                                             

Mecp2tm3.1Bird
methyl CpG binding protein 2; targeted mutation 3.1, Adrian Bird                             X    MECP2-EGFP                                         Targeted (Reporter)               no abnormal phenotype observed                                                                                                                                                                                  

Mecp2tm3.1Jae
methyl CpG binding protein 2; targeted mutation 3.1, Rudolf Jaenisch                          X    Mecp2S421A;S424A                                   Targeted (knock-in)               behavior, nervous system                                                                                                                                                                                        

Mecp2tm1a(EUCOMM)Wtsi
methyl CpG binding protein 2; targeted mutation 1a, Wellcome Trust Sanger Institute   X                                                       Targeted (Floxed/Frt)
(Cell Line)