Symbol Name ID

Ryr2 ryanodine receptor 2, cardiac MGI:99685

---

17 matching Alleles (1 Gene/Marker represented)

---

                                          Allele Symbol
Name                                             Chr        Synonyms                    Category                                               Phenotypic Classes                                                                                                                                   Human Diseases                                                                                                 

Ryr2tm1.1Clhh
ryanodine receptor 2, cardiac; targeted mutation 1.1, Christopher Huang                    13   RyR2P2328S, RyR2s     Targeted (knock-in)               cardiovascular                                                                       Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, with or without Atrial Dysfunction and/or Dilated Cardiomyopathy; CPVT1 604772                                                                       

Ryr2tm1.1Hta
ryanodine receptor 2, cardiac; targeted mutation 1.1, Hiroshi Takeshima                     13   Crrm2                 Targeted (knock-out)              cardiovascular, embryogenesis, growth/size, mortality/aging, muscle                                                                                                                                                                                                                                  

Ryr2tm1.1Maya
ryanodine receptor 2, cardiac; targeted mutation 1.1, Masafumi Yano                        13   RyR2 R2474S           Targeted (knock-in)               cardiovascular, homeostasis                                                          Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, with or without Atrial Dysfunction and/or Dilated Cardiomyopathy; CPVT1 604772                                                                       

Ryr2tm1.1Msnr
ryanodine receptor 2, cardiac; targeted mutation 1.1, Gerhard Meissner                     13   Ryr2ADA, Ryr2tm1Msnr  Targeted (knock-in)               cardiovascular, growth/size, mortality/aging, muscle                                                                                                                                                                                                                                                 

Ryr2tm1.1Swch
ryanodine receptor 2, cardiac; targeted mutation 1.1, S R Wayne Chen
                       13   R4496C                Targeted (knock-in)               cardiovascular, homeostasis                                                                                                                                                                                                                                                                          

Ryr2tm1.1Wex
ryanodine receptor 2, cardiac; targeted mutation 1.1, Xander Wehrens                        13   Ryr2S2814A            Targeted (knock-in)               cardiovascular, homeostasis                                                                                                                                                                                                                                                                          

Ryr2tm1Amks
ryanodine receptor 2, cardiac; targeted mutation 1, Andrew R Marks                           13   RyR2-S2808A           Targeted (knock-in)               cardiovascular, homeostasis                                                                                                                                                                                                                                                                          

Ryr2tm1Hhv
ryanodine receptor 2, cardiac; targeted mutation 1, Hector H Valdivia                         13   RyR2-S2808A           Targeted (knock-in)               no abnormal phenotype observed                                                                                                                                                                                                                                                                       

Ryr2tm1Hta
ryanodine receptor 2, cardiac; targeted mutation 1, Hiroshi Takeshima                         13   Crrm1                 Targeted (Floxed/Frt)             no abnormal phenotype observed                                                                                                                                                                                                                                                                       

Ryr2tm1Maya
ryanodine receptor 2, cardiac; targeted mutation 1, Masafumi Yano                            13   RyR2R2474S-neo        Targeted (knock-in)                                                                                                                                                                                                                                                                                                                    

Ryr2tm1Nobs
ryanodine receptor 2, cardiac; targeted mutation 1, Noboru Suzuki                            13                         Targeted (knock-out)              immune, muscle, tumorigenesis                                                                                                                                                                                                                                                                        

Ryr2tm1Sgp
ryanodine receptor 2, cardiac; targeted mutation 1, Silvia G Priori                           13   Ryr2R4496C            Targeted (knock-in)               cardiovascular                                                                       Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, with or without Atrial Dysfunction and/or Dilated Cardiomyopathy; CPVT1 604772                                                                       

Ryr2tm1Slh
ryanodine receptor 2, cardiac; targeted mutation 1, Susan L Hamilton
                          13   Ryr2R176Q             Targeted (knock-in)               cardiovascular, homeostasis, muscle                                                  Arrhythmogenic Right Ventricular Dysplasia, Familial, 2; ARVD2 600996; Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, with or without Atrial Dysfunction and/or Dilated Cardiomyopathy; CPVT1 604772

Ryr2tm2.1Maya
ryanodine receptor 2, cardiac; targeted mutation 2.1, Masafumi Yano                        13   RyR2S2246L            Targeted (knock-in)               cardiovascular                                                                                                                                                                                                                                                                                       

Ryr2tm2Amks
ryanodine receptor 2, cardiac; targeted mutation 2, Andrew R Marks                           13   Ryr2-R2474S           Targeted (knock-in)               behavior, cardiovascular, growth/size, homeostasis, mortality/aging, nervous system                                                                                                                                                                                                                  

Ryr2tm1a(KOMP)Wtsi
ryanodine receptor 2, cardiac; targeted mutation 1a, Wellcome Trust Sanger Institute  13                         Targeted (Floxed/Frt)
(Cell Line)                                                                                                                                                                                                                                                                                                       

Ryr2tm1e(KOMP)Wtsi
ryanodine receptor 2, cardiac; targeted mutation 1e, Wellcome Trust Sanger Institute  13                         Targeted (Reporter)
(Cell Line)