Symbol Name ID

Chuk conserved helix-loop-helix ubiquitous kinase MGI:99484

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11 matching Alleles (1 Gene/Marker represented)

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                                                   Allele Symbol
Name                                                      Chr       Synonyms                   Category                                                                                                          Phenotypic Classes                                                                                                  Human Diseases    

Chuktm1.1Mpa
conserved helix-loop-helix ubiquitous kinase; targeted mutation 1.1, Manolis Pasparakis                       19                       Targeted (knock-out)             cellular, craniofacial, digestive/alimentary, integument, limbs/digits/tail, mortality/aging, skeleton                                                                                                                             

Chuktm1Aki
conserved helix-loop-helix ubiquitous kinase; targeted mutation 1, Shizuo Akira                                 19   IKKalpha-           Targeted (knock-out)             cellular, craniofacial, embryogenesis, homeostasis, integument, limbs/digits/tail, mortality/aging, skeleton                                                                                                 Cocoon Syndrome 613630

Chuktm1Lex
conserved helix-loop-helix ubiquitous kinase; targeted mutation 1, Lexicon Genetics                             19   IKKalphafl          Targeted (Floxed/Frt)            cellular, immune                                                                                                                                                                                                                   

Chuktm1Mka
conserved helix-loop-helix ubiquitous kinase; targeted mutation 1, Michael Karin                                19   Ikka-, Ikkalpha-    Targeted (Reporter)              cardiovascular, cellular, craniofacial, digestive/alimentary, embryogenesis, growth/size, hearing/vestibular/ear, immune, integument, limbs/digits/tail, mortality/aging, respiratory, skeleton, vision/eye  Cocoon Syndrome 613630

Chuktm1Mpa
conserved helix-loop-helix ubiquitous kinase; targeted mutaion 1, Manolis Pasparakis                            19   Ikk1FL              Targeted (Floxed/Frt)            cellular, endocrine/exocrine, growth/size, homeostasis, immune, integument, liver/biliary, mortality/aging                                                                                                                         

Chuktm1Ver
conserved helix-loop-helix ubiquitous kinase; targeted mutation 1, Inder M Verma                                19   IKK1-               Targeted (knock-out)             cellular, craniofacial, digestive/alimentary, embryogenesis, endocrine/exocrine, growth/size, homeostasis, integument, limbs/digits/tail, liver/biliary, mortality/aging, skeleton                           Cocoon Syndrome 613630

Chuktm1Yhu
conserved helix-loop-helix ubiquitous kinase; targeted mutation 1, Yinling Hu                                   19   IkkalphaF           Targeted (Floxed/Frt)            cellular, digestive/alimentary, growth/size, integument, mortality/aging, skeleton, tumorigenesis, vision/eye                                                                                                                      

Chuktm2Mka
conserved helix-loop-helix ubiquitous kinase; targeted mutation 2, Michael Karin                                19   IkkaAA, IKKalphaAA  Targeted (knock-in)              endocrine/exocrine, immune, integument, reproductive                                                                                                                                                                               

Chuktm1e(KOMP)Wtsi
conserved helix-loop-helix ubiquitous kinase; targeted mutation 1e, Wellcome Trust Sanger Institute     19                       Targeted (Reporter)
(Cell Line)                                                                                                                                                                                                                                      

Chuktm1(NCOM)Mfgc
conserved helix-loop-helix ubiquitous kinase; targeted mutation 1, Mammalian Functional Genomics Centre  19                       Targeted (knock-out)
(Cell Line)                                                                                                                                                                                                                                     

Chuktm2e(KOMP)Wtsi
conserved helix-loop-helix ubiquitous kinase; targeted mutation 2e, Wellcome Trust Sanger Institute     19                       Targeted (Reporter)
(Cell Line)