Symbol Name ID

Notch2 notch 2 MGI:97364

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14 matching Alleles (1 Gene/Marker represented)

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                                 Allele Symbol
Name                                    Chr               Synonyms                          Category                                                                                                                Phenotypic Classes                                                                                                                Human Diseases           

Notch2tm1.1(cre/ERT2)Sat
notch 2; targeted mutation 1.1, Spyros Artavanis-Tsakonas     3    N2-CreERT2SAT                      Targeted (knock-in)               mortality/aging                                                                                                                                                                                                                                              

Notch2tm1Bmc
notch 2; targeted mutation 1, Brent McCright                              3    Notch2N1in                         Targeted (knock-in)               no abnormal phenotype observed                                                                                                                                                                                                                               

Notch2tm1Frad
notch 2; targeted mutation 1, Freddy Radtke                              3    N2-, Notch1f, Notch2flox           Targeted (Floxed/Frt)             cellular, digestive/alimentary, endocrine/exocrine, hematopoietic, immune, integument, pigmentation                                                                                                                                                          

Notch2tm1Grid
notch 2; targeted mutation 1, Tom Gridley                                3    Notch2-, Notch2del1                Targeted (knock-out)              cardiovascular, cellular, embryogenesis, endocrine/exocrine, growth/size, homeostasis, integument, liver/biliary, mortality/aging, muscle, renal/urinary, vision/eye                                                                                         

Notch2tm1Hhi
notch 2; targeted mutation 1, Hisamaru Hirai                              3    Notch2f                            Targeted (Floxed/Frt)             cellular, hematopoietic, immune                                                                                                                                                                                                                              

Notch2tm1Rko
notch 2; targeted mutation 1, Raphael Kopan                               3    N2flox                             Targeted (Floxed/Frt)             endocrine/exocrine, hematopoietic, immune, integument, mortality/aging, tumorigenesis                                                                                                                                                                        

Notch2tm1Yha
notch 2; targeted mutation 1, Yoshio Hamaha                               3    N2LacZ, Notch2m                    Targeted (Reporter)               cardiovascular, cellular, embryogenesis, growth/size, hematopoietic, immune, mortality/aging                                                                                                                                                                 

Notch2tm2Grid
notch 2; targeted mutation 2, Tom Gridley                                3    Notch2del2                         Targeted (knock-out)              cardiovascular, embryogenesis, endocrine/exocrine, growth/size, homeostasis, immune, liver/biliary, mortality/aging                                                                                                                                          

Notch2tm2Hhi
notch 2; targeted mutation 2, Hisamaru Hirai                              3    Notch2-                            Targeted (knock-out)              cellular, hematopoietic, immune, mortality/aging                                                                                                                                                                                                             

Notch2tm3.1Grid
notch 2; targeted mutation 3.1, Tom Gridley                            3    Notch2del3                         Targeted (knock-out)              cardiovascular, craniofacial, embryogenesis, endocrine/exocrine, growth/size, homeostasis, liver/biliary, mortality/aging, muscle                                                                                                                            

Notch2tm3Grid
notch 2; targeted mutation 3, Tom Gridley                                3    N2f, N2flox, Notch2Fl, Notch2flox  Targeted (Floxed/Frt)             cardiovascular, cellular, craniofacial, embryogenesis, endocrine/exocrine, growth/size, homeostasis, liver/biliary, mortality/aging, muscle, nervous system, renal/urinary, reproductive, respiratory, taste/olfaction  Preeclampsia/Eclampsia 1; PEE1 189800

Notch2tm1a(EUCOMM)Wtsi
notch 2; targeted mutation 1a, Wellcome Trust Sanger Institute  3                                       Targeted (Floxed/Frt)
(Cell Line)                                                                                                                                                                                                                                                               

Notch2tm1e(EUCOMM)Wtsi
notch 2; targeted mutation 1e, Wellcome Trust Sanger Institute  3                                       Targeted (Reporter)
(Cell Line)                                                                                                                                                                                                                                                                 

Notch2tm1(KOMP)Vlcg
notch 2; targeted mutation 1, Velocigene                           3                                       Targeted (knock-out)
(Cell Line)