Symbol
Name
ID
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Synonyms
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9930111A19Rik, lin-12, Mis6, Motch A, Tan1
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(46)
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Alleles
and
phenotypes
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All alleles(26) :
Targeted, knock-out(5)
Targeted, other(5)
Gene trapped(16)
| Homozygotes for targeted null alleles exhibit defects in angiogenic vascular remodeling, and impaired somitogenesis with extensive cell death resulting in lethality by embryonic day 11.5. |
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Polymorphisms
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RFLP(5)
SNPs within 2kb(316 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (247 records)
Data Summary:
Assays (51)
Results (356)
Tissues (222)
Images (147)
Theiler Stages: 1,4,5,9,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,28
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Assay Type |
Assays |
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Results |
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Western blot |
3 |
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9 |
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RT-PCR |
8 |
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73 |
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RNA in situ |
32 |
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228 |
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Immunohistochemistry |
4 |
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17 |
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Northern blot |
2 |
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8 |
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RNase protection |
2 |
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21 |
cDNA source data(29)
External Resources:
Allen Brain Atlas
GENSAT
GEO
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Molecular
reagents
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All nucleic(65)
Genomic(6)
cDNA(35)
Primer pair(10)
Other(14)
Antibodies(6)
Microarray probesets(3)
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Other database
links
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Protein
domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:31835
Weinmaster G et al.,
"A homolog of Drosophila Notch expressed during mammalian development."
Development 1991 Sep;113(1):199-205
(Latest)
J:153642
Vlangos CN et al.,
"Caudal regression in adrenocortical dysplasia (acd) mice is caused by telomere dysfunction with subsequent p53-dependent apoptosis."
Dev Biol 2009 Oct 15;334(2):418-28
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All references(418)
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Other
accession IDs
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MGD-MRK-12915, MGD-MRK-18791, MGI:1915375
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