Symbol
Name
ID
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Synonyms
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C230052L06Rik, HGF/SF, NK1, NK2, scatter factor, SF/HGF
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(34)
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Alleles
and
phenotypes
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All alleles(3) :
Targeted, knock-out(2)
Targeted, other(1)
| Homozygotes for targeted null mutations exhibit reduced embryonic livers, impaired migration of dermomyotome precursors affecting skeletal muscle formation, defective navigation of hypoglossal motor axons, abnormal placentas, and prenatal lethality. |
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Polymorphisms
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RFLP(2)
SNPs within 2kb(498 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (43 records)
Data Summary:
Assays (23)
Results (360)
Tissues (181)
Images (38)
Theiler Stages: 14,15,16,17,18,19,20,21,22,23,24,25,26,28
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Assay Type |
Assays |
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Results |
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Western blot |
1 |
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1 |
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RT-PCR |
8 |
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211 |
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RNA in situ |
4 |
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110 |
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Immunohistochemistry |
2 |
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7 |
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Northern blot |
7 |
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24 |
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RNase protection |
1 |
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7 |
cDNA source data(31)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
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All nucleic(51)
Genomic(10)
cDNA(32)
Primer pair(7)
Other(2)
Antibodies(4)
Microarray probesets(3)
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Other database
links
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Protein
domains
|
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:909
Szpirer C et al.,
"Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF)."
Genomics 1992 Jun;13(2):293-300
(Latest)
J:154237
Schultz JM et al.,
"Noncoding mutations of HGF are associated with nonsyndromic hearing loss, DFNB39."
Am J Hum Genet 2009 Jul;85(1):25-39
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All references(108)
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Other
accession IDs
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MGD-MRK-10704, MGI:2443459
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