Symbol
Name
ID
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Synonyms
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D230004K18Rik, Gp330, Megalin
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(36)
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Alleles
and
phenotypes
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All alleles(16) :
Targeted, knock-out(1)
Targeted, other(1)
Gene trapped(13)
Chemically induced(1)
| Homozygotes for a targeted null mutation exhibit lung and kidney epithelial defects, impaired B12 uptake, reduced proliferation of the neuroepithelium resulting in lack of olfactory bulbs, forebrain fusions, ventricular defects, and perinatal lethality. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
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Polymorphisms
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All PCR and RFLP(3) :
PCR(1)
RFLP(2)
SNPs within 2kb(1158 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (19 records)
Data Summary:
Assays (4)
Results (8)
Tissues (4)
Images (2)
Theiler Stages: 9,19,24,26
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Assay Type |
Assays |
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Results |
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Immunohistochemistry |
4 |
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8 |
cDNA source data(123)
External Resources:
Allen Brain Atlas
GENSAT
GEO
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Molecular
reagents
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All nucleic(127)
Genomic(1)
cDNA(125)
Primer pair(1)
Antibodies(3)
Microarray probesets(3)
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Other database
links
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Protein
domains
|
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:14575
Xia YR et al.,
"Mapping of the glycoprotein 330 (Gp330) gene to mouse chromosome 2."
Genomics 1993 Sep;17(3):780-1
(Latest)
J:151683
Parreira KS et al.,
"Expression patterns of the aquaporin gene family during renal development: influence of genetic variability."
Pflugers Arch 2009 Aug;458(4):745-59
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All references(67)
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Other
accession IDs
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MGD-MRK-10218, MGI:2138891, MGI:2139361, MGI:2444234
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