Symbol
Name
ID
|
|
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Synonyms
|
DII B, Dlx, Dlx-1
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Genetic Map
|
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Sequence Map
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Mammalian
homology
|
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Sequences
|
All sequences(19)
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Alleles
and
phenotypes
|
All alleles(2) :
Targeted, knock-out(2)
| Homozygous null mutants show morphogenetic abnormalities in first and second branchial arch-derived proximal skeletal and soft tissue structures; in double mutants with a Dlx2 null allele, maxillary molar teeth are missing. |
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Polymorphisms
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SNPs within 2kb(40 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
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Expression
|
Literature Summary: (105 records)
Data Summary:
Assays (35)
Results (230)
Tissues (115)
Images (75)
Theiler Stages: 13,14,15,16,17,18,19,20,21,22,23,24,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
1 |
|
2 |
| |
RNA in situ |
23 |
|
178 |
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Immunohistochemistry |
2 |
|
20 |
| |
Northern blot |
4 |
|
11 |
| |
RNase protection |
5 |
|
19 |
cDNA source data(15)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(29)
Genomic(6)
cDNA(15)
Primer pair(1)
Other(7)
Antibodies(1)
Microarray probesets(2)
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Other database
links
|
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Protein
domains
|
Graphical View
of Protein Domain Structure
|
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References
|
(Earliest)
J:11292
Price M et al.,
"A mouse gene related to Distal-less shows a restricted expression in the developing forebrain."
Nature 1991 Jun 27;351(6329):748-51
(Latest)
J:151894
Oishi K et al.,
"Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1."
Proc Natl Acad Sci U S A 2009 Aug 4;106(31):13064-9
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All references(133)
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Other
accession IDs
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MGD-MRK-8857, MGD-MRK-8861
|
