Symbol
Name
ID
|
|
|
Synonyms
|
Comt2, F930017I19Rik
|
|
Genetic Map
|
|
Chromosome 7
|
Syntenic
|
|
|
|
Mapping data(
1)
|
|
|
|
Sequence Map
|
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Mammalian
homology
|
|
|
Sequences
|
All sequences(10)
|
Alleles
and
phenotypes
|
All alleles(4) :
Gene trapped(3)
Chemically induced(1)
| Mice homozygous for a mutation of this gene exhibit marked hyperactivity, bidirectional circling and head-tossing. These behaviors are suppressed during sleep and nursing. Homozygous mutant males exhibit heightened male:male aggression. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
|
|
Polymorphisms
|
SNPs within 2kb(27 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
cDNA source data(2)
|
Molecular
reagents
|
All nucleic(2)
cDNA(2)
|
|
Pathways
|
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Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR002935 |
O-methyltransferase, family 3 |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:86696
Zambrowicz BP et al.,
"Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention."
Proc Natl Acad Sci U S A 2003 Nov 25;100(24):14109-14
(Latest)
J:137493
Du X et al.,
"A catechol-O-methyltransferase that is essential for auditory function in mice and humans"
Proc Natl Acad Sci U S A 2008;105(38):14609-14
|
All references(3)
|
Other
accession IDs
|
MGI:3707696
|
