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Myh14 Gene Detail
 Symbol
Name
ID
Myh14
myosin, heavy polypeptide 14
MGI:1919210


Nomenclature History
Synonyms 2400004E04Rik, NMHC II-C
Genetic Map
Chromosome 7
cytoband B2
 
Mapping data( 2)
Sequence Map
Chr7:51861173-51926213 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; rat    (Mammalian Orthology)
Protein SuperFamily: myosin heavy chain
TreeFam: TF333601
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000017593 VEGA Gene Model | MGI Sequence Detail 65041 C57BL/6J ± Kb
transcript NM_028021 RefSeq | MGI Sequence Detail 6376 C57BL/6
polypeptide Q6URW6 UniProt | EBI | MGI Sequence Detail 2000 Not Applicable
For the selected sequences
All sequences(23)
Alleles
and
phenotypes
All alleles(4) : Gene trapped(4)
Polymorphisms SNPs within 2kb(276 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(16)
Process actin filament-based movement, regulation of cell shape...
Component axon, cytoplasm...
Function actin binding, actin filament binding...
External Resources: MouseFunc
Expression Literature Summary: (7 records)
Data Summary: Assays (8)    Results (33)    Tissues (20)    Images (8)
Theiler Stages: 20,24,28
  Assay Type Assays   Results
      Western blot 1   1
      RT-PCR 7   32
cDNA source data(39)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(41) cDNA(39) Primer pair(2) Antibodies(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000030739
DoTS DT.101723482, DT.40143047, DT.91327954
UniGene 158289
DFCI TC1582128, TC1624335
NIA Mouse Gene Index U028495
Entrez Gene 71960
VEGA Gene Model OTTMUSG00000017593
International Mouse Knockout Project Status Myh14
Protein
domains
InterPro ID Description
IPR000048 IQ calmodulin-binding region
IPR001609 Myosin head, motor domain
IPR002928 Myosin tail
IPR004009 Myosin, N-terminal, SH3-like
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J et al., "Functional annotation of a full-length mouse cDNA collection." Nature 2001 Feb 8;409(6821):685-90
(Latest) J:149772 Jana SS et al., "An alternatively spliced isoform of non-muscle myosin II-C is not regulated by myosin light chain phosphorylation." J Biol Chem 2009 Apr 24;284(17):11563-71
All references(13)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory