About   Help   FAQ
Ighmbp2 Gene Detail
 Symbol
Name
ID
Ighmbp2
immunoglobulin mu binding protein 2
MGI:99954


Nomenclature History
Synonyms AEP, Catf1, p110 subunit, RIPE3b1, sma, Smbp-2, Smbp2, Smubp2
Genetic Map
Chromosome 19
0.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 5)

Sequence Map
Chr19:3260924-3283017 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat; hamster, golden    (Mammalian Orthology)
Comparative Map (Mouse/Human Ighmbp2 ± 2 cM)
TreeFam: TF105388
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000028273 VEGA Gene Model | MGI Sequence Detail 22094 C57BL/6J ± Kb
transcript NM_009212 RefSeq | MGI Sequence Detail 5562 -
polypeptide P40694 UniProt | EBI | MGI Sequence Detail 993 Not Applicable
For the selected sequences
All sequences(22)
Alleles
and
phenotypes
All alleles(8) : Gene trapped(6) Spontaneous(2)
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (1)  
Polymorphisms RFLP(1) SNPs within 2kb(65 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(30)
Process protein homooligomerization, regulation of transcription...
Component axon, cell projection...
Function ATP binding, DNA binding...
External Resources: MouseFunc
Expression Literature Summary: (2 records)
Data Summary: Assays (7)    Results (42)    Tissues (26)    Images (2)
Theiler Stages: 17,18,21,23,26,28
  Assay Type Assays   Results
      Western blot 3   21
      RNA in situ 2   17
      Immunohistochemistry 2   4
cDNA source data(32)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(41) Genomic(8) cDNA(33) Antibodies(2)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000024831
UniGene 3179
DFCI TC1579804, TC1603503
NIA Mouse Gene Index U019116
Entrez Gene 20589
VEGA Gene Model OTTMUSG00000028273
International Mouse Knockout Project Status Ighmbp2
Protein
domains
InterPro ID Description
IPR000058 Zinc finger, AN1-type
IPR001374 Single-stranded nucleic acid binding R3H
IPR003593 ATPase, AAA+ type, core
IPR004483 DNA helicase, putative
IPR014001 DEAD-like helicase, N-terminal
Graphical View of Protein Domain Structure
References
(Earliest) J:4973 Mizuta TR et al., "Isolation of cDNA encoding a binding protein specific to 5'-phosphorylated single-stranded DNA with G-rich sequences." Nucleic Acids Res 1993 Apr 25;21(8):1761-6
(Latest) J:148546 de Planell-Saguer M et al., "Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery." Hum Mol Genet 2009 Jun 15;18(12):2115-26
All references(23)
Other
accession IDs
MGD-MRK-14446, MGD-MRK-16062, MGD-MRK-16757, MGI:99301

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/20/2009
MGI_4.31
Web browser compatibility
The Jackson Laboratory