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Arrb2 Gene Detail
 Symbol
Name
ID
Arrb2
arrestin, beta 2
MGI:99474

Nomenclature History
Synonyms beta arr2, beta-arrestin-2, beta-arrestin2
Genetic Map
Chromosome 11
45.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 3)

Sequence Map
Chr11:70246137-70254330 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Arrb2 ± 2 cM)
Protein SuperFamily: arrestin
TreeFam: TF314260
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000006049 VEGA Gene Model | MGI Sequence Detail 8194 C57BL/6J ± Kb
transcript NM_145429 RefSeq | MGI Sequence Detail 1728 C57BL/6
polypeptide Q91YI4 UniProt | EBI | MGI Sequence Detail 410 Not Applicable
For the selected sequences
All sequences(26)
Alleles
and
phenotypes 		All alleles(3) : Targeted, knock-out(1) Gene trapped(2)
Polymorphisms RFLP(1) SNPs within 2kb(46 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process negative regulation of signal transduction, protein transport...
Component coated pit, cytoplasm...
Function protein binding
External Resources: FuncBase
Expression Literature Summary: (1 records)
cDNA source data(44)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(47) Genomic(1) cDNA(46)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000060216
DoTS DT.530327, DT.94333420, DT.97382835, DT.99858083
Consensus CDS Project CCDS24946.1
UniGene 203747
DFCI TC1581135, TC1631013
NIA Mouse Gene Index U012849
Entrez Gene 216869
VEGA Gene Model OTTMUSG00000006049
International Mouse Knockout Project Status Arrb2
Protein
domains
InterPro ID Description
IPR000698 Arrestin
IPR011021 Arrestin-like, N-terminal
IPR011022 Arrestin-like, C-terminal
IPR014752 Arrestin, C-terminal
IPR014753 Arrestin, N-terminal
IPR014756 Immunoglobulin E-set
IPR017864 Arrestin, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:13280 Shinohara T et al., "A family of retinal S-antigens (arrestins) and their genes: comparative analysis of human, mouse, rat, bovine and Drosophila." Comp Biochem Physiol B Biochem Mol Biol 1992 Nov;103(3):505-9
(Latest) J:155523 Li Y et al., "Regulation of amygdalar PKA by {beta}-arrestin-2/phosphodiesterase-4 complex is critical for fear conditioning." Proc Natl Acad Sci U S A 2009 Dec 2;():
All references(53)
Other
accession IDs 		MGD-MRK-16248, MGI:2144136, MGI:2144500
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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