Symbol
Name
ID
|
|
|
STS
|
D6Rck2
|
|
Synonyms
|
2610510E18Rik, Int1l1, Irp, m-irp, Mirp, Wnt-2, Wnt2a
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Genetic Map
|
|
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Sequence Map
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Mammalian
homology
|
|
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Sequences
|
All sequences(19)
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Alleles
and
phenotypes
|
All alleles(4) :
Targeted, knock-out(1)
Targeted, other(3)
| Homozygous mutants exhibit impaired placental vascularization, runting and 50% perinatal mortality resulting from difficulties in breathing and nursing. Survivors of the perinatal period tend to recover, and adults are healthy and fertile. |
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Polymorphisms
|
All PCR and RFLP(3) :
PCR(2)
RFLP(1)
SNPs within 2kb(243 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (52 records)
Data Summary:
Assays (25)
Results (243)
Tissues (171)
Images (32)
Theiler Stages: 1,2,3,4,5,8,9,11,12,13,15,17,19,20,21,22,23,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
9 |
|
43 |
| |
RNA in situ |
10 |
|
159 |
| |
Immunohistochemistry |
1 |
|
2 |
| |
Northern blot |
4 |
|
37 |
| |
RNase protection |
1 |
|
2 |
cDNA source data(17)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
|
All nucleic(47)
Genomic(13)
cDNA(18)
Primer pair(11)
Other(5)
Antibodies(1)
Microarray probesets(2)
|
Other database
links
|
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Protein
domains
|
|
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References
|
(Earliest)
J:9380
Wainwright BJ et al.,
"Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless."
EMBO J 1988 Jun;7(6):1743-8
(Latest)
J:153785
Warner DR et al.,
"Expression of Wnts in the developing murine secondary palate."
Int J Dev Biol 2009;53(7):1105-12
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All references(71)
|
Other
accession IDs
|
MGD-MRK-11475, MGD-MRK-15439, MGD-MRK-15449, MGI:1919406
|
