Symbol
Name
ID
|
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Synonyms
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Int-1, Wnt-1
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Genetic Map
|
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(14)
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Alleles
and
phenotypes
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All alleles(4) :
Targeted, knock-out(3)
Spontaneous(1)
| In mild form, homozygotes have ataxia and hypertonia, with malformation of anterior cerebellum, deep midline fissure, and impaired fertility. In the severe form, there is virtually no midbrain and cerebellum and mutants die within hours of birth. |
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Polymorphisms
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All PCR and RFLP(14) :
PCR(2)
RFLP(12)
SNPs within 2kb(54 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
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Expression
|
Literature Summary: (193 records)
Data Summary:
Assays (68)
Results (611)
Tissues (268)
Images (126)
Theiler Stages: 1,2,3,4,5,8,9,11,12,13,14,15,16,17,19,20,21,22,23,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
8 |
|
122 |
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RNA in situ |
52 |
|
438 |
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Immunohistochemistry |
1 |
|
4 |
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Northern blot |
6 |
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45 |
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RNase protection |
1 |
|
2 |
cDNA source data(25)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(82)
Genomic(10)
cDNA(30)
Primer pair(10)
Other(32)
Antibodies(1)
Microarray probesets(2)
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Other database
links
|
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Protein
domains
|
Graphical View
of Protein Domain Structure
|
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References
|
(Earliest)
J:15063
Lane PW,
"Swaying"
Mouse News Lett 1967;36():40
(Latest)
J:152847
Prakash N et al.,
"Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain."
Development 2009 Aug;136(15):2545-55
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All references(323)
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Other
accession IDs
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MGD-MRK-11418, MGD-MRK-14669, MGD-MRK-15438, MGD-MRK-15448
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