Symbol
Name
ID
|
|
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Synonyms
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Tpi-1
|
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Genetic Map
|
|
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Sequence Map
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Mammalian
homology
|
|
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Sequences
|
All sequences(46)
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Alleles
and
phenotypes
|
All alleles(7) :
Gene trapped(2)
Chemically induced(5)
| Homozygous null mutants die at postimplantation stage. Heterozygotes are normal, but with 50% of normal enzyme activity. Mice heterozygous or homozygous for a hyperactivity allele have 140 and 190% enzyme activity, respectively, but are otherwise normal. |
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Polymorphisms
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RFLP(7)
SNPs within 2kb(16 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
|
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Expression
|
Literature Summary: (5 records)
Data Summary:
Assays (4)
Results (150)
Tissues (112)
Images (23)
Theiler Stages: 15,17,22,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
1 |
|
2 |
| |
RNA in situ |
2 |
|
140 |
| |
Northern blot |
1 |
|
8 |
cDNA source data(21)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
|
All nucleic(31)
Genomic(4)
cDNA(23)
Primer pair(2)
Other(2)
Microarray probesets(3)
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Pathways
|
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Other database
links
|
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Protein
domains
|
| InterPro ID |
Description |
| IPR000652 |
Triosephosphate isomerase |
| IPR013785 |
Aldolase-type TIM barrel |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:5946
Kozak CA et al.,
"Assignment of the genes for thymidine kinase and galactokinase to Mus musculus chromosome 11 and the preferential segregation of this chromosome in Chinese hamster/mouse somatic cell hybrids."
Somatic Cell Genet 1977 Mar;3(2):121-33
(Latest)
J:125993
Cankaya M et al.,
"An analysis of expression patterns of genes encoding proteins with catalytic activities."
BMC Genomics 2007;8():232
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All references(40)
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Other
accession IDs
|
MGD-MRK-15179, MGD-MRK-15180, MGI:2141384
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