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Sox11 Gene Detail
 Symbol
Name
ID
Sox11
SRY-box containing gene 11
MGI:98359

Nomenclature History
Synonyms 1110038H03Rik, 6230403H02Rik, end1
Genetic Map
Chromosome 12
cytoband A3
 
Mapping data( 3)
Sequence Map
Chr12:28019129-28027439 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; rat    (Mammalian Orthology)
Protein SuperFamily: SOX-12/11/4a protein
TreeFam: TF316183
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000021163 VEGA Gene Model | MGI Sequence Detail 8311 C57BL/6J ± Kb
transcript NM_009234 RefSeq | MGI Sequence Detail 8451 C57BL/6
polypeptide Q7M6Y2 UniProt | EBI | MGI Sequence Detail 395 Not Applicable
For the selected sequences
All sequences(47)
Alleles
and
phenotypes 		All alleles(1) : Targeted, other(1)
Homozygous null mice display neonatal lethality with impaired ossification and impaired development of the heart, lung, spleen, stomach, skeleton, and pancreas.
Polymorphisms SNPs within 2kb(47 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(11)
Process cell differentiation, multicellular organismal development...
Component nucleus
Function DNA binding, RNA polymerase II transcription factor activity, enhancer binding...
External Resources: MouseFunc
Expression Literature Summary: (29 records)
Data Summary: Assays (12)    Results (222)    Tissues (190)    Images (37)
Theiler Stages: 11,15,16,17,20,21,22,23,24,26,28
  Assay Type Assays   Results
      RT-PCR 4   63
      RNA in situ 7   157
      Northern blot 1   2
cDNA source data(21)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents 		All nucleic(30) cDNA(25) Primer pair(5)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000063632
DoTS DT.103571478, DT.525047, DT.529295, DT.94260399, DT.99841910
DFCI TC1579106, TC1586225, TC1596797, TC1604073, TC1639944, TC1650282, TC1665342, TC1777221
NIA Mouse Gene Index U070418, U367574
Entrez Gene 20666
VEGA Gene Model OTTMUSG00000021163
International Mouse Knockout Project Status Sox11
Protein
domains
InterPro ID Description
IPR000910 High mobility group, HMG1/HMG2
IPR009071 High mobility group, superfamily
IPR017386 SOX-12/11/4a
Graphical View of Protein Domain Structure
References
(Earliest) J:4011 Wright EM et al., "Seven new members of the Sox gene family expressed during mouse development." Nucleic Acids Res 1993 Feb 11;21(3):744
(Latest) J:149242 Cameron TL et al., "Global comparative transcriptome analysis of cartilage formation in vivo." BMC Dev Biol 2009;9():20
All references(39)
Other
accession IDs 		MGD-MRK-14498, MGI:1913439, MGI:1915029, MGI:2144888
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/20/2009
MGI_4.31
Web browser compatibility 		The Jackson Laboratory