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Plaur Gene Detail
 Symbol
Name
ID
Plaur
plasminogen activator, urokinase receptor
MGI:97612


Nomenclature History
Synonyms Cd87, u-PAR, uPAR, urokinase-type plasminogen activator receptor
Genetic Map
Chromosome 7
cytoband A3
 
Mapping data( 2)
Sequence Map
Chr7:25247519-25260893 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: urokinase plasminogen activator surface receptor
TreeFam: TF338662
Sequences
Representative Sequences Length Strain/Species Flank
genomic 18793 NCBI Gene Model | MGI Sequence Detail 13375 C57BL/6J ± Kb
transcript NM_011113 RefSeq | MGI Sequence Detail 1396 -
polypeptide P35456 UniProt | EBI | MGI Sequence Detail 327 Not Applicable
For the selected sequences
All sequences(27)
Alleles
and
phenotypes
All alleles(4) : Targeted, knock-out(2) Gene trapped(2)
Polymorphisms SNPs within 2kb(57 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(6)
Component anchored to membrane, extracellular region...
Function kinase activity, receptor activity...
External Resources: MouseFunc
Expression Literature Summary: (7 records)
Data Summary: Assays (3)    Results (17)    Tissues (17)    Images (1)
Theiler Stages: 1,2,3,4,11,13,15,17,19,20,21,22,28
  Assay Type Assays   Results
      RT-PCR 3   17
cDNA source data(32)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(36) Genomic(2) cDNA(32) Primer pair(2)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000046223
DoTS DT.101400634, DT.94308654, DT.97412079
UniGene 1359
DFCI TC1581513, TC1588678, TC1653385
NIA Mouse Gene Index U007797
Entrez Gene 18793
International Mouse Knockout Project Status Plaur
Protein
domains
InterPro ID Description
IPR001526 CD59 antigen
IPR016054 Ly-6 antigen / uPA receptor -like
IPR018363 CD59 antigen, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:2322 Kristensen P et al., "Two alternatively spliced mouse urokinase receptor mRNAs with different histological localization in the gastrointestinal tract." J Cell Biol 1991 Dec;115(6):1763-71
(Latest) J:149754 Tjwa M et al., "Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells." J Clin Invest 2009 Apr;119(4):1008-18
All references(62)
Other
accession IDs
MGD-MRK-13348

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory