Symbol
Name
ID
|
|
|
Synonyms
|
Pk-2, Pk-3, Pk3
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(69)
|
Alleles
and
phenotypes
|
All alleles(127) :
Gene trapped(127)
| Co-dominant electrophoretic variants are: C57BL and most inbreds have slow anodal bands (a allele); IS/Cam and Peru have faster migrating bands (b allele). A third mutant activity allele arose in C57BL and is prenatal lethal in homozygotes; heterozygotes have about 50% activity in kidney and heart. |
|
|
Polymorphisms
|
SNPs within 2kb(130 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (7 records)
Data Summary:
Assays (9)
Results (169)
Tissues (108)
Images (21)
Theiler Stages: 22,24,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
3 |
|
18 |
| |
RNA in situ |
4 |
|
129 |
| |
Northern blot |
2 |
|
22 |
cDNA source data(30)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(37)
cDNA(31)
Primer pair(6)
Microarray probesets(2)
|
|
Pathways
|
|
Other database
links
|
| EC |
2.7.1.40 |
| Ensembl Gene Model |
ENSMUSG00000032294 |
| DoTS |
DT.101225700, DT.101242555, DT.102552948, DT.110615414, DT.87073803, DT.91431037, DT.97353754, DT.97391543, DT.97391559, DT.97391564, DT.99872554 |
| DFCI |
TC1573623, TC1755768 |
| NIA Mouse Gene Index |
U010583, U096926 |
| Entrez Gene |
18746 |
| International Mouse Knockout Project Status |
Pkm2 |
|
Protein
domains
|
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:5994
Lalley PA et al.,
"Conservation of autosomal gene synteny groups in mouse and man."
Nature 1978 Jul 13;274(5667):160-3
(Latest)
J:149737
Sansom SN et al.,
"The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis."
PLoS Genet 2009 Jun;5(6):e1000511
|
All references(35)
|
Other
accession IDs
|
MGD-MRK-13319, MGD-MRK-13320, MGD-MRK-13322, MGI:2143183, MGI:2143184, MGI:2144733
|
