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Oca2 Gene Detail
 Symbol
Name
ID
Oca2
oculocutaneous albinism II
MGI:97454


Nomenclature History
Synonyms D7H15S12, D7H15S12, p
Genetic Map
Chromosome 7
28.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 144)

Sequence Map
Chr7:63495130-63791887 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Oca2 ± 2 cM)
TreeFam: TF323556
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000025863 VEGA Gene Model | MGI Sequence Detail 296758 C57BL/6J ± Kb
transcript NM_021879 RefSeq | MGI Sequence Detail 3120 C57BL/6
polypeptide Q62052 UniProt | EBI | MGI Sequence Detail 833 Not Applicable
For the selected sequences
All sequences(12)
Alleles
and
phenotypes
All alleles(66) : Gene trapped(1) Spontaneous(19) Chemically induced(7) Radiation induced(39)
Mutations generally result in varying degrees of coat and eye pigment dilution. Specific alleles produce cleft palate, reproductive, endocrine or neurological disorders, and/or lethality.
Phenotype Images (3)  
Polymorphisms All PCR and RFLP(15) : PCR(2) RFLP(13) SNPs within 2kb(1827 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(14)
Process cell proliferation, citrate transport...
Component integral to membrane, membrane...
Function arsenite transmembrane transporter activity, citrate transmembrane transporter activity...
External Resources: MouseFunc
Expression Literature Summary: (3 records)
Data Summary: Assays (1)    Results (2)    Tissues (1)    Images (1)
Theiler Stages: 28
  Assay Type Assays   Results
      RT-PCR 1   2
cDNA source data(8)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents
All nucleic(25) Genomic(10) cDNA(12) Primer pair(3)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000030450
DoTS DT.60103690
UniGene 137052
DFCI TC1584133
NIA Mouse Gene Index U008156
Entrez Gene 18431
VEGA Gene Model OTTMUSG00000025863
International Mouse Knockout Project Status Oca2
Protein
domains
InterPro ID Description
IPR000802 Arsenical pump membrane protein
IPR004680 Divalent ion symporter
Graphical View of Protein Domain Structure
References
(Earliest) J:100 Haldane JBS et al., "Reduplication in mice" J Genet 1915;5():133-135
(Latest) J:148390 Reliene R et al., "N-acetyl cysteine protects against ionizing radiation-induced DNA damage but not against cell killing in yeast and mammals." Mutat Res 2009 Jun 1;665(1-2):37-43
All references(206)
Other
accession IDs
MGD-MRK-13097, MGD-MRK-7793, MGD-MRK-7817, MGD-MRK-8115

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory