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Odc1 Gene Detail
 Symbol
Name
ID
Odc1
ornithine decarboxylase, structural 1
MGI:97402


Nomenclature History
STS D12Nds11
Synonyms ODC
Genetic Map
Chromosome 12
6.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 35)

Sequence Map
Chr12:17551778-17557890 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; hamster, Chinese; rat; sheep    (Mammalian Orthology)
Comparative Map (Mouse/Human Odc1 ± 2 cM)
Protein SuperFamily: ornithine decarboxylase
TreeFam: TF300760
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000011179 Ensembl Gene Model | MGI Sequence Detail 6113 C57BL/6J ± Kb
transcript NM_013614 RefSeq | MGI Sequence Detail 2547 -
polypeptide P00860 UniProt | EBI | MGI Sequence Detail 461 Not Applicable
For the selected sequences
All sequences(65)
Alleles
and
phenotypes
All alleles(7) : Targeted, other(1) Gene trapped(6)
Homozygous null embryos die prior to gastrulation.
Polymorphisms All PCR and RFLP(5) : PCR(1) RFLP(4) SNPs within 2kb(41 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(9)
Process kidney development, polyamine biosynthetic process...
Component cytosol
Function carboxy-lyase activity, catalytic activity...
External Resources: MouseFunc
Expression Literature Summary: (13 records)
Data Summary: Assays (2)    Results (4)    Tissues (2)
Theiler Stages: 4
  Assay Type Assays   Results
      In situ reporter (knock in) 1   2
      Immunohistochemistry 1   2
cDNA source data(24)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents
All nucleic(34) Genomic(6) cDNA(25) Primer pair(2) Other(1) Antibodies(1)
Microarray probesets(2)
Pathways
spermine biosynthesis II
putrescine biosynthesis III
Other database
links
EC 4.1.1.17
Ensembl Gene Model ENSMUSG00000011179
DoTS DT.101392287, DT.101738463, DT.40162581, DT.537268
PDB 7ODC
DFCI TC1573105, TC1676513
NIA Mouse Gene Index U005821, U013795, U056224, U068130, U076823, U078885, U109938, U127084, U163034, U365943
Entrez Gene 18263
International Mouse Knockout Project Status Odc1
Protein
domains
InterPro ID Description
IPR000183 Orn/DAP/Arg decarboxylase 2
IPR002433 Ornithine decarboxylase
IPR009006 Alanine racemase/group IV decarboxylase, C-terminal
Graphical View of Protein Domain Structure
References
(Earliest) J:7845 Janne OA et al., "Ornithine decarboxylase mRNA in mouse kidney: a low abundancy gene product regulated by androgens with rapid kinetics." Ann N Y Acad Sci 1984;438():72-84
(Latest) J:146741 Lopez-Garcia C et al., "Transcriptomic analysis of polyamine-related genes and polyamine levels in placenta, yolk sac and fetus during the second half of mouse pregnancy." Placenta 2009 Mar;30(3):241-9
All references(90)
Other
accession IDs
MGD-MRK-12979

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory