Symbol
Name
ID
|
|
|
Synonyms
|
iNOS, Nos-2, NOS-II, Nos2a
|
|
Genetic Map
|
|
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Sequence Map
|
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Mammalian
homology
|
|
|
Sequences
|
All sequences(22)
|
Alleles
and
phenotypes
|
All alleles(4) :
Targeted, knock-out(3)
Gene trapped(1)
Associated Human Diseases (2)
Alleles Annotated to Human Diseases (2)
Phenotype Images (1)
|
|
Polymorphisms
|
RFLP(7)
SNPs within 2kb(141 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (32 records)
Data Summary:
Assays (11)
Results (218)
Tissues (61)
Images (6)
Theiler Stages: 13,15,19,20,21,23,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
Western blot |
1 |
|
6 |
| |
RT-PCR |
9 |
|
206 |
| |
RNase protection |
1 |
|
6 |
cDNA source data(26)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
|
All nucleic(40)
Genomic(4)
cDNA(29)
Primer pair(6)
Other(1)
Antibodies(1)
Microarray probesets(2)
|
|
Pathways
|
|
Other database
links
|
| EC |
1.14.13.39 |
| Ensembl Gene Model |
ENSMUSG00000020826 |
| DoTS |
DT.527028 |
| UniGene |
2893 |
| PDB |
1DD7, 1DF1, 1DWV, 1DWW, 1DWX, 1JWJ, 1JWK, 1M8D, 1M8E, 1M8H, 1M8I, 1M9T, 1N2N, 1NOC, 1NOD, 1NOS, 1QOM, 1QW4, 1QW5, 1R35, 1VAF, 2BHJ, 2NOD, 2NOS, 2ORO, 2ORP, 2ORQ, 2ORR, 2ORS, 2ORT, 3DWJ, 3E65, 3E67, 3E68, 3E6L, 3E6N, 3E6O, 3E6T, 3E7I, 3E7M, 3E7T, 3EAI, 3EBD, 3EBF, 3NOD |
| DFCI |
TC1585345 |
| NIA Mouse Gene Index |
U040163 |
| Entrez Gene |
18126 |
| VEGA Gene Model |
OTTMUSG00000000146 |
| International Mouse Knockout Project Status |
Nos2 |
|
Protein
domains
|
| InterPro ID |
Description |
| IPR001094 |
Flavodoxin-like |
| IPR001433 |
Oxidoreductase FAD/NAD(P)-binding |
| IPR001709 |
Flavoprotein pyridine nucleotide cytochrome reductase |
| IPR003097 |
FAD-binding, type 1 |
| IPR004030 |
Nitric oxide synthase, oxygenase domain |
| IPR008254 |
Flavodoxin/nitric oxide synthase |
| IPR012144 |
Nitric-oxide synthase |
| IPR017927 |
Ferredoxin reductase-type FAD-binding domain |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:1868
Liew FY et al.,
"Resistance to Leishmania major infection correlates with the induction of nitric oxide synthase in murine macrophages."
Eur J Immunol 1991 Dec;21(12):3009-14
(Latest)
J:152797
Gorbunov NV et al.,
"Up-regulation of autophagy in small intestine Paneth cells in response to total-body gamma-irradiation."
J Pathol 2009 Oct;219(2):242-52
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All references(542)
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Other
accession IDs
|
MGD-MRK-12910, MGD-MRK-12913
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