Symbol
Name
ID
|
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Synonyms
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Mtapt, Tau
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
|
All sequences(52)
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Alleles
and
phenotypes
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All alleles(326) :
Targeted, knock-out(3)
Targeted, other(11)
Gene trapped(312)
| Homozygous mutants exhibit altered performance in behavioral tests and show mircotubule changes in small-calibre axons. Embryonic hippocampal cultures from mutants exhibit delayed axonal and neuritic maturation. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
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Polymorphisms
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SNPs within 2kb(431 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
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Expression
|
Literature Summary: (25 records)
Data Summary:
Assays (12)
Results (49)
Tissues (10)
Images (1)
Theiler Stages: 17,22,23,25,26,28
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Assay Type |
Assays |
|
Results |
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Western blot |
9 |
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39 |
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RT-PCR |
2 |
|
8 |
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RNA in situ |
1 |
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2 |
cDNA source data(20)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
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All nucleic(26)
Genomic(4)
cDNA(20)
Primer pair(2)
Antibodies(9)
Microarray probesets(4)
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Other database
links
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| Ensembl Gene Model |
ENSMUSG00000018411 |
| DoTS |
DT.101204582, DT.101383559, DT.101383564, DT.101714060, DT.528743, DT.91341342, DT.97351013 |
| DFCI |
TC1577412, TC1582042, TC1591009, TC1595991, TC1619579, TC1621917, TC1665909 |
| NIA Mouse Gene Index |
U013429 |
| Entrez Gene |
17762 |
| VEGA Gene Model |
OTTMUSG00000003153 |
| International Mouse Knockout Project Status |
Mapt |
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Protein
domains
|
Graphical View
of Protein Domain Structure
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References
|
(Earliest)
J:17288
Drubin DG et al.,
"Studies on the expression of the microtubule-associated protein, tau, during mouse brain development, with newly isolated complementary DNA probes."
J Cell Biol 1984 Mar;98(3):1090-7
(Latest)
J:154023
Nam HS et al.,
"High levels of Id1 expression define B1 type adult neural stem cells."
Cell Stem Cell 2009 Nov 6;5(5):515-26
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All references(113)
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Other
accession IDs
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MGD-MRK-12590, MGD-MRK-14720, MGI:2144146, MGI:2144478
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