Symbol
Name
ID
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|
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Synonyms
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B/MMP9, Clg4b, Gel B, Gelatinase B, gelatinase B, MMP-9
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(27)
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Alleles
and
phenotypes
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All alleles(4) :
Targeted, knock-out(4)
| Null mutants have short long bones with compensatory growth via delayed ossification and apoptosis of hypertrophic chondroctyes. Mutants are protected against ischemic brain injury, damage caused by myocardial infarction, and allergic airway inflammation. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
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Polymorphisms
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All PCR and RFLP(2) :
PCR(1)
RFLP(1)
SNPs within 2kb(89 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (87 records)
Data Summary:
Assays (22)
Results (68)
Tissues (37)
Images (15)
Theiler Stages: 1,2,3,4,11,17,19,20,21,22,23,24,26,28
| |
Assay Type |
Assays |
|
Results |
| |
Western blot |
1 |
|
3 |
| |
RT-PCR |
11 |
|
39 |
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RNA in situ |
7 |
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14 |
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Immunohistochemistry |
2 |
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8 |
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Northern blot |
1 |
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4 |
cDNA source data(20)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(38)
Genomic(3)
cDNA(21)
Primer pair(10)
Other(4)
Antibodies(3)
Microarray probesets(3)
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Other database
links
|
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Protein
domains
|
Graphical View
of Protein Domain Structure
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References
|
(Earliest)
J:3961
Tanaka H et al.,
"Molecular cloning and expression of the mouse 105-kDa gelatinase cDNA."
Biochem Biophys Res Commun 1993 Feb 15;190(3):732-40
(Latest)
J:153449
Sabeh F et al.,
"Secreted versus membrane-anchored collagenases: relative roles in fibroblast-dependent collagenolysis and invasion."
J Biol Chem 2009 Aug 21;284(34):23001-11
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All references(285)
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Other
accession IDs
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MGD-MRK-12281, MGD-MRK-2014, MGI:2139414
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