Symbol
Name
ID
|
|
|
Synonyms
|
LTA4 hydrodase
|
|
Genetic Map
|
|
Chromosome 10
|
cytoband C3
|
|
|
|
Mapping data(
2)
|
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(29)
|
Alleles
and
phenotypes
|
All alleles(3) :
Targeted, knock-out(1)
Gene trapped(2)
| Mice homozygous for disruptions in this gene have grossly normal phenotypes. Inflammatory reactions are reduced as are some other immunological responses. |
|
|
Polymorphisms
|
SNPs within 2kb(151 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (1 records)
Data Summary:
Assays (1)
Results (93)
Tissues (93)
Images (15)
Theiler Stages: 22
| |
Assay Type |
Assays |
|
Results |
| |
RNA in situ |
1 |
|
93 |
cDNA source data(147)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
|
All nucleic(150)
cDNA(149)
Primer pair(1)
Microarray probesets(1)
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR001930 |
Peptidase M1, membrane alanine aminopeptidase |
| IPR006025 |
Peptidase M, neutral zinc metallopeptidases, zinc-binding site |
| IPR012777 |
Leukotriene A-4 hydrolase/aminopeptidase |
| IPR014782 |
Peptidase M1, membrane alanine aminopeptidase, N-terminal |
| IPR015211 |
Peptidase M1, leukotriene A4 hydrolase, aminopeptidase C-terminal |
| IPR016024 |
Armadillo-type fold |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:11211
Medina JF et al.,
"Molecular cloning and expression of mouse leukotriene A4 hydrolase cDNA."
Biochem Biophys Res Commun 1991 May 15;176(3):1516-24
(Latest)
J:148535
Zarini S et al.,
"Transcellular biosynthesis of cysteinyl leukotrienes in vivo during mouse peritoneal inflammation."
Proc Natl Acad Sci U S A 2009 May 19;106(20):8296-301
|
All references(14)
|
Other
accession IDs
|
MGD-MRK-11898
|
