Symbol
Name
ID
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Lrpap1
low density lipoprotein receptor-related protein associated protein 1
MGI:96829
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Nomenclature History
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Synonyms
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RAP
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(49)
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Alleles
and
phenotypes
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All alleles(21) :
Targeted, knock-out(2)
Gene trapped(19)
| Mice homozygous for disruptions in this gene display an essentially normal phenotype. However, subtle abnormalities are seen in behavior, brain function and thyroid function. |
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Polymorphisms
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RFLP(1)
SNPs within 2kb(110 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (5 records)
Data Summary:
Assays (9)
Results (30)
Tissues (3)
Images (9)
Theiler Stages: 28
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Assay Type |
Assays |
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Results |
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Northern blot |
9 |
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30 |
cDNA source data(252)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
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All nucleic(256)
Genomic(3)
cDNA(253)
Microarray probesets(4)
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Other database
links
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Protein
domains
|
| InterPro ID |
Description |
| IPR000886 |
Endoplasmic reticulum, targeting sequence motif |
| IPR009066 |
Alpha-2-macroglobulin receptor-associated protein, domain 1 |
| IPR010483 |
Alpha-2-macroglobulin RAP, C-terminal |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:18372
Furukawa T et al.,
"A heparin binding protein whose expression increases during differentiation of embryonal carcinoma cells to parietal endoderm cells: cDNA cloning and sequence analysis."
J Biochem 1990 Aug;108(2):297-302
(Latest)
J:143942
Xu G et al.,
"Receptor-associated protein (RAP) plays a central role in modulating Abeta deposition in APP/PS1 transgenic mice."
PLoS ONE 2008;3(9):e3159
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All references(43)
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Other
accession IDs
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MGD-MRK-11887, MGI:2140781, MGI:2140964, MGI:2141085, MGI:2141295
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