Symbol
Name
ID
|
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Synonyms
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Ins-2, InsII, Mody, Mody4
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(28)
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Alleles
and
phenotypes
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All alleles(118) :
Targeted, knock-out(2)
Targeted, other(7)
Gene trapped(107)
Spontaneous(1)
Chemically induced(1)
| Mice homozygous for spontaneous or knock-out alleles exhibit increased mortality, abnormal growth, abnormal glucose homeostasis, impaired pancreatic function, and phenotypes associated with type 2 diabetes. |
Associated Human Diseases (4)
Alleles Annotated to Human Diseases (2)
Phenotype Images (3)
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Polymorphisms
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All PCR and RFLP(6) :
PCR(3)
RFLP(3)
SNPs within 2kb(31 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (199 records)
Data Summary:
Assays (46)
Results (241)
Tissues (106)
Images (81)
Theiler Stages: 2,3,5,11,13,14,15,16,17,18,19,20,21,22,23,24,25,26,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
24 |
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166 |
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RNA in situ |
3 |
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8 |
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Immunohistochemistry |
19 |
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67 |
cDNA source data(139)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
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All nucleic(189)
Genomic(30)
cDNA(139)
Primer pair(17)
Other(3)
Antibodies(10)
Microarray probesets(2)
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Other database
links
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Protein
domains
|
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:6658
Goldfeld AE et al.,
"Genetic control of insulin receptors."
Proc Natl Acad Sci U S A 1981 Oct;78(10):6359-61
(Latest)
J:154092
Jones MJ et al.,
"An imprinted GFP insertion reveals long-range epigenetic regulation in embryonic lineages."
Dev Biol 2009 Dec 1;336(1):42-52
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All references(325)
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Other
accession IDs
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MGD-MRK-11411, MGD-MRK-11414, MGD-MRK-39550, MGI:109551, MGI:2141856
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