Symbol
Name
ID
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Synonyms
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C5, C5a, He
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(18)
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Alleles
and
phenotypes
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All alleles(2) :
Spontaneous(1)
Other(1)
| Macrophage from mice homozygous for disruptions of this gene do not secrete complement C5.
The 2 bp deletion found in A/J and AKR/J strains is associated with susceptibility to allergen-induced bronchial hyperresponsiveness and is a candidate for QTL Abhr2. |
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Polymorphisms
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All PCR and RFLP(14) :
PCR(1)
RFLP(13)
SNPs within 2kb(327 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (1 records)
Data Summary:
Assays (1)
Results (41)
Tissues (30)
Theiler Stages: 16,18,20,21,23,25,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
1 |
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41 |
cDNA source data(35)
External Resources:
Allen Brain Atlas
GEO
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Molecular
reagents
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All nucleic(49)
Genomic(11)
cDNA(35)
Primer pair(2)
Other(1)
Microarray probesets(2)
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Other database
links
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Protein
domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:12959
HERZENBERG LA et al.,
"A gene locus concerned with hemolytic complement in Mus musculus."
Genetics 1963 May;48():711-5
(Latest)
J:146538
Miwa T et al.,
"Complement-dependent T-cell lymphopenia caused by thymocyte deletion of the membrane complement regulator Crry."
Blood 2009 Mar 19;113(12):2684-94
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All references(153)
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Other
accession IDs
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MGD-MRK-10645, MGD-MRK-10689, MGD-MRK-1703
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