Symbol
Name
ID
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Synonyms
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H-2T18, TL Ag, Tla
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(17)
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Alleles
and
phenotypes
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| This locus controls presence of a cell surface antigen on thymic and intestinal epithelium. Among inbred strains at least 5 alleles are known determining different antigenic specificities, as well as an allele determining absence of antigen. C57BL/6 mice carry a deletion of this gene. |
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Polymorphisms
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RFLP(7)
SNPs within 2kb(24 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (1 records)
cDNA source data(1)
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Molecular
reagents
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All nucleic(24)
Genomic(19)
cDNA(2)
Other(3)
Microarray probesets(2)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR001039 |
MHC class I, alpha chain, alpha1/alpha2 |
| IPR003006 |
Immunoglobulin/major histocompatibility complex, conserved site |
| IPR003597 |
Immunoglobulin C1-set |
| IPR007110 |
Immunoglobulin-like |
| IPR011161 |
MHC class I-like antigen recognition |
| IPR011162 |
MHC classes I/II-like antigen recognition protein |
| IPR013783 |
Immunoglobulin-like fold |
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References
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(Earliest)
J:13118
BOYSE EA et al.,
"GENETIC DETERMINATION OF THE TL (THYMUSLEUKAEMIA) ANTIGEN IN THE MOUSE."
Nature 1964 Feb 22;201():779
(Latest)
J:142515
Olivares-Villagomez D et al.,
"Thymus leukemia antigen controls intraepithelial lymphocyte function and inflammatory bowel disease."
Proc Natl Acad Sci U S A 2008 Nov 18;105(46):17931-6
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All references(50)
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Other
accession IDs
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MGD-MRK-10433, MGD-MRK-10546, MGD-MRK-15131
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