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H2-Q1 Gene Detail
 Symbol
Name
ID
H2-Q1
histocompatibility 2, Q region locus 1
MGI:95928


Nomenclature History
STS D17Mit47,D17Rua9
Synonyms H-2Q1, Q1, Q1b, Q1d, Q1k
Genetic Map
Chromosome 17
19.14 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 8)

Sequence Map
Chr17:35457507-35462364 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human H2-Q1 ± 2 cM)
Protein SuperFamily: class I histocompatibility antigen
TreeFam: TF336617
Sequences
Representative Sequences Length Strain/Species Flank
genomic 15006 NCBI Gene Model | MGI Sequence Detail 4858 C57BL/6J ± Kb
transcript NM_010390 RefSeq | MGI Sequence Detail 2044 C57BL/6
polypeptide NP_034520 RefSeq | MGI Sequence Detail 368 C57BL/6
For the selected sequences
All sequences(23)
Polymorphisms RFLP(3) SNPs within 2kb(68 from dbSNP Build 128)   SNPs within 2kb including multiple locations(76)
Gene Ontology
(GO)
classifications
All GO classifications(5)
Process antigen processing and presentation of peptide antigen via MHC class I, immune response...
Component integral to membrane, membrane...
External Resources: MouseFunc
Expression Literature Summary: (2 records)
Data Summary: Assays (2)    Results (24)    Tissues (20)    Images (2)
Theiler Stages: 15,19,20,22,28
  Assay Type Assays   Results
      RT-PCR 2   24
cDNA source data(3)
External Resources: GENSAT  GEO 
Molecular
reagents
All nucleic(29) Genomic(23) cDNA(4) Primer pair(1) Other(1)
Microarray probesets(2)
Other database
links
NIA Mouse Gene Index U378791
Entrez Gene 15006
International Mouse Knockout Project Status H2-Q1
Protein
domains
InterPro ID Description
IPR001039 MHC class I, alpha chain, alpha1/alpha2
IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like
IPR010579 MHC class I, alpha chain, C-terminal
IPR011161 MHC class I-like antigen recognition
IPR011162 MHC classes I/II-like antigen recognition protein
IPR013783 Immunoglobulin-like fold
References
(Earliest) J:6148 Hammerling GJ et al., "Qat-4 and Qat-5, new murine T-cell antigens governed by the Tla region and identified by monoclonal antibodies." J Exp Med 1979 Jul 1;150(1):108-16
(Latest) J:137349 Swanson PA nd et al., "An MHC class Ib-restricted CD8 T cell response confers antiviral immunity." J Exp Med 2008 Jul 7;205(7):1647-57
All references(18)
Other
accession IDs
MGD-MRK-10412, MGD-MRK-10524, MGD-MRK-13708, MGD-MRK-13718, MGD-MRK-13736, MGI:3779428

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/20/2009
MGI_4.31
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