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H2-D1 Gene Detail
 Symbol
Name
ID
H2-D1
histocompatibility 2, D region locus 1
MGI:95896


Nomenclature History
STS D17Rua7
Synonyms H-2D, H-2D
Genetic Map
Chromosome 17
19.09 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 60)

Sequence Map
Chr17:35400039-35404440 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
Protein SuperFamily: class I histocompatibility antigen
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000073411 Ensembl Gene Model | MGI Sequence Detail 4402 C57BL/6J ± Kb
transcript U47326 GenBank | EMBL | DDBJ | MGI Sequence Detail 1586 BALB/c
polypeptide P14427 UniProt | EBI | MGI Sequence Detail 368 Not Applicable
For the selected sequences
All sequences(37)
Alleles
and
phenotypes
All alleles(3) : Targeted, knock-out(1) Spontaneous(2)
Polymorphisms RFLP(20) SNPs within 2kb(46 from dbSNP Build 128)   SNPs within 2kb including multiple locations(94)
Gene Ontology
(GO)
classifications
All GO classifications(12)
Process antigen processing and presentation, antigen processing and presentation of peptide antigen via MHC class I...
Component external side of plasma membrane, integral to membrane...
Function protein binding
External Resources: MouseFunc
Expression Literature Summary: (4 records)
Data Summary: Assays (5)    Results (82)    Tissues (64)    Images (3)
Theiler Stages: 1,2,3,4,15,19,20,22,23,28
  Assay Type Assays   Results
      RT-PCR 4   77
      Immunohistochemistry 1   5
cDNA source data(11)
Molecular
reagents
All nucleic(113) Genomic(93) cDNA(14) Primer pair(4) Other(2) Antibodies(1)
Microarray probesets(6)
Other database
links
Ensembl Gene Model ENSMUSG00000073411
PDB 1BII, 1DDH, 1QO3, 3DMM, 3E6F, 3E6H, 3ECB
International Mouse Knockout Project Status H2-D1
Protein
domains
InterPro ID Description
IPR001039 MHC class I, alpha chain, alpha1/alpha2
IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like
IPR010579 MHC class I, alpha chain, C-terminal
IPR011161 MHC class I-like antigen recognition
IPR011162 MHC classes I/II-like antigen recognition protein
IPR013783 Immunoglobulin-like fold
Graphical View of Protein Domain Structure
References
(Earliest) J:106349 Melvold RW et al., "Eight new histocompatibility mutations associated with the H-2 complex" Immunogenetics 1976;3():185-191
(Latest) J:154072 Felio K et al., "CD1-restricted adaptive immune responses to Mycobacteria in human group 1 CD1 transgenic mice." J Exp Med 2009 Oct 26;206(11):2497-509
All references(172)
Other
accession IDs
MGD-MRK-10379, MGD-MRK-10492

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory