H2 Complex/Cluster/Region Detail
Symbol
Name
ID
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Synonyms
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H-2, MHC-II
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Genetic Map
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Alleles
and
phenotypes
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All alleles(14) :
Targeted, knock-out(1)
Spontaneous(1)
Other(12)
| The H2 complex contains 3 major classes of highly polymorphic gene sets: class I (H2-K, H2-D, Q, H2-T18 genes), class II (H2-I genes), and class III (H2-S genes). These genes are involved in many processes, including graft rejection, immune response, antigen presentation and complement component. |
Associated Human Diseases (2)
Alleles Annotated to Human Diseases (3)
Phenotype Images (2)
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Polymorphisms
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RFLP(12)
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Expression
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Literature Summary: (3 records)
cDNA source data(5)
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Molecular
reagents
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All nucleic(10)
cDNA(8)
Other(2)
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Other database
links
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References
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(Earliest)
J:301
Snell GD,
"Preliminary data on crossing-over between H-2, and Fu, Ki and T in the mouse"
Heredity 1952;6():247-54
(Latest)
J:153788
Garcia-Ceca J et al.,
"On the role of Eph signalling in thymus histogenesis; EphB2/B3 and the organizing of the thymic epithelial network."
Int J Dev Biol 2009;53(7):971-82
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All references(486)
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Other
accession IDs
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MGD-MRK-10366, MGD-MRK-10489
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