About   Help   FAQ
Tour our new Quick Search
H13 Gene Detail
 Symbol
Name
ID
H13
histocompatibility 13
MGI:95886

Nomenclature History
Synonyms 1200006O09Rik, 4930443L17Rik, 5031424B04Rik, H-13, Spp
Genetic Map
Chromosome 2
86.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 10)

Sequence Map
Chr2:152495197-152534406 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human H13 ± 2 cM)
TreeFam: TF105854
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000015824 VEGA Gene Model | MGI Sequence Detail 39210 C57BL/6J ± Kb
transcript NM_001159551 RefSeq | MGI Sequence Detail 5402 C57BL/6
polypeptide Q9D8V0 UniProt | EBI | MGI Sequence Detail 378 Not Applicable
For the selected sequences
All sequences(68)
Alleles
and
phenotypes 		All alleles(28) : Gene trapped(28)
This is one of several loci identified by development of congenic strains differing in resistance to transplantable tumors. C57BL/10 carries the a allele and B10.129(14M) carries the b allele.
Polymorphisms RFLP(1) SNPs within 2kb(227 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(8)
Component endoplasmic reticulum, endoplasmic reticulum membrane...
Function aspartic-type endopeptidase activity, hydrolase activity...
External Resources: MouseFunc
Expression Literature Summary: (2 records)
Data Summary: Assays (5)    Results (54)    Tissues (18)
Theiler Stages: 10,18,23,25,28
  Assay Type Assays   Results
      RT-PCR 3   26
      RNA in situ 2   28
cDNA source data(175)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents 		All nucleic(181) Genomic(1) cDNA(176) Primer pair(4)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000019188
DoTS DT.101710625, DT.495217, DT.55275604, DT.94178805, DT.94359034, DT.97401570, DT.97401571
UniGene 277327
PDB 1INQ, 1JUF
DFCI TC1573047, TC1584248, TC1587865, TC1588110, TC1589010
NIA Mouse Gene Index U002650
Entrez Gene 14950
VEGA Gene Model OTTMUSG00000015824
International Mouse Knockout Project Status H13
Protein
domains
InterPro ID Description
IPR006639 Peptidase A22, presenilin signal peptide
IPR007369 Peptidase A22B, signal peptide peptidase
Graphical View of Protein Domain Structure
References
(Earliest) J:5026 Graff RJ et al., "Histocompatibility genes of mice. VI. Allografts in mice congenic at various non-H-2 histocompatibility loci." Transplantation 1966 Jul;4(4):425-37
(Latest) J:114602 Urny J et al., "Cell-surface expression of a new splice variant of the mouse signal peptide peptidase." Biochim Biophys Acta 2006 Mar-Apr;1759(3-4):159-65
All references(22)
Other
accession IDs 		MGD-MRK-10359, MGD-MRK-10481, MGI:1914866, MGI:1915400, MGI:2139237, MGI:2447815
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
11/20/2009
MGI_4.31
Web browser compatibility 		The Jackson Laboratory