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Slc2a4 Gene Detail
 Symbol
Name
ID
Slc2a4
solute carrier family 2 (facilitated glucose transporter), member 4
MGI:95758


Nomenclature History
STS D11Mit15
Synonyms Glut-4, Glut4
Genetic Map
Chromosome 11
40.0 cM, cytoband C-E1
Detailed Genetic Map ± 1 cM
 
Mapping data( 11)

Sequence Map
Chr11:69756045-69761690 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Slc2a4 ± 2 cM)
Protein SuperFamily: glucose transport protein
TreeFam: TF313762
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000006028 VEGA Gene Model | MGI Sequence Detail 5646 C57BL/6J ± Kb
transcript NM_009204 RefSeq | MGI Sequence Detail 2822 C57BL/6
polypeptide P14142 UniProt | EBI | MGI Sequence Detail 509 Not Applicable
For the selected sequences
All sequences(23)
Alleles
and
phenotypes
All alleles(5) : Targeted, knock-out(1) Targeted, other(4)
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (1)  
Polymorphisms PCR(3) SNPs within 2kb(46 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(30)
Process brown fat cell differentiation, carbohydrate transport...
Component cytoplasm, cytoplasmic vesicle membrane...
Function glucose transmembrane transporter activity, insulin-responsive hydrogen:glucose symporter activity...
External Resources: MouseFunc
Expression Literature Summary: (12 records)
Data Summary: Assays (7)    Results (111)    Tissues (56)    Images (4)
Theiler Stages: 11,13,15,17,20,22,23,24,25,26,28
  Assay Type Assays   Results
      RT-PCR 4   95
      Northern blot 3   16
cDNA source data(46)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(59) Genomic(3) cDNA(48) Primer pair(5) Other(3)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000018566
DoTS DT.532441, DT.91335589, DT.91411894
UniGene 10661
DFCI TC1576122
NIA Mouse Gene Index U158646
Entrez Gene 20528
VEGA Gene Model OTTMUSG00000006028
International Mouse Knockout Project Status Slc2a4
Protein
domains
InterPro ID Description
IPR002441 Glucose transporter, type 4 (GLUT4)
IPR003663 Sugar/inositol transporter
IPR005828 General substrate transporter
IPR005829 Sugar transporter, conserved site
IPR016196 Major facilitator superfamily, general substrate transporter
Graphical View of Protein Domain Structure
References
(Earliest) J:4901 Fan YS et al., "Assignment of genes encoding three human glucose transporter/transporter-like proteins (GLUT4, GLUT5 and GLUT6) to chromosomes 17, 1 and 5 respectively" Cytogenet Cell Genet 1989;51():997
(Latest) J:142614 Nedachi T et al., "Contractile C2C12 myotube model for studying exercise-inducible responses in skeletal muscle." Am J Physiol Endocrinol Metab 2008 Nov;295(5):E1191-204
All references(136)
Other
accession IDs
MGD-MRK-10158, MGD-MRK-10162

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
11/20/2009
MGI_4.31
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