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Glra1 Gene Detail
 Symbol
Name
ID
Glra1
glycine receptor, alpha 1 subunit
MGI:95747


Nomenclature History
Synonyms B230397M16Rik, nmf11, oscillator, ot
Genetic Map
Chromosome 11
30.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 18)

Sequence Map
Chr11:55327740-55421700 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Glra1 ± 2 cM)
Protein SuperFamily: acetylcholine receptor
TreeFam: TF315453
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000005698 VEGA Gene Model | MGI Sequence Detail 93961 C57BL/6J ± Kb
transcript NM_020492 RefSeq | MGI Sequence Detail 1407 C57BL/6
polypeptide Q64018 UniProt | EBI | MGI Sequence Detail 457 Not Applicable
For the selected sequences
All sequences(29)
Alleles
and
phenotypes
All alleles(6) : Targeted, other(2) Spontaneous(3) Chemically induced(1)
Mutations in this gene result in neurological defects for all alleles reported. Specific alleles also show affects on viability, reproductive performance, and/or eye and respiratory physiology.
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (3)  
Polymorphisms All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(230 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(52)
Process acrosome reaction, adult walking behavior...
Component cell junction, chloride channel complex...
Function chloride channel activity, chloride ion binding...
This is a GO Consortium Reference Genome Project gene.
External Resources: MouseFunc
Expression Literature Summary: (1 records)
Data Summary: Assays (1)    Results (1)    Tissues (1)
Theiler Stages: 23
  Assay Type Assays   Results
      RNA in situ 1   1
cDNA source data(6)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(14) Genomic(5) cDNA(7) Primer pair(1) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000000263
DoTS DT.91329697
UniGene 89320
DFCI TC1590970, TC1621269
NIA Mouse Gene Index U032792
Entrez Gene 14654
VEGA Gene Model OTTMUSG00000005698
International Mouse Knockout Project Status Glra1
Protein
domains
InterPro ID Description
IPR006028 Gamma-aminobutyric acid A receptor
IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
IPR006201 Neurotransmitter-gated ion-channel
IPR006202 Neurotransmitter-gated ion-channel ligand-binding
IPR008127 Glycine receptor alpha
IPR008128 Glycine receptor alpha1
IPR018000 Neurotransmitter-gated ion-channel, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:13463 Dickie MM, "Oscillator." Mouse News Lett 1967;36():39
(Latest) J:132622 Weiss J et al., "Glycinergic input of small-field amacrine cells in the retinas of wildtype and glycine receptor deficient mice." Mol Cell Neurosci 2008 Jan;37(1):40-55
All references(43)
Other
accession IDs
MGD-MRK-10130, MGD-MRK-13058, MGD-MRK-14516, MGI:2429917, MGI:2444829

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory