Symbol
Name
ID
|
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Synonyms
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Ghrfr
|
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Genetic Map
|
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Sequence Map
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Mammalian
homology
|
|
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Sequences
|
All sequences(18)
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Alleles
and
phenotypes
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All alleles(2) :
Targeted, knock-out(1)
Spontaneous(1)
| Homozygotes for a spontaneous null mutation exhibit reduced growth from 2 weeks of age, impaired growth hormone synthesis and release, obesity, decreased bone mass, reduced fertility in males, impaired first lactations, and extended life span. |
Phenotype Images (2)
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Polymorphisms
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All PCR and RFLP(3) :
PCR(2)
RFLP(1)
SNPs within 2kb(70 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
|
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Expression
|
Literature Summary: (6 records)
cDNA source data(4)
External Resources:
Allen Brain Atlas
GEO
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Molecular
reagents
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All nucleic(10)
Genomic(3)
cDNA(5)
Primer pair(2)
Microarray probesets(2)
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Other database
links
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Protein
domains
|
| InterPro ID |
Description |
| IPR000832 |
GPCR, family 2, secretin-like |
| IPR001879 |
GPCR, family 2, extracellular hormone receptor domain |
| IPR003288 |
GPCR, family 2, growth hormone-releasing hormone receptor |
| IPR017981 |
GPCR, family 2-like |
| IPR017983 |
GPCR, family 2, secretin-like, conserved site |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:64445
Eicher EM,
"lit - little"
Mouse News Lett 1972;47():36
(Latest)
J:146582
Swindell WR,
"Accelerated failure time models provide a useful statistical framework for aging research."
Exp Gerontol 2009 Mar;44(3):190-200
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All references(79)
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Other
accession IDs
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MGD-MRK-10072, MGD-MRK-10074, MGD-MRK-11813
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