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Fabp2 Gene Detail
 Symbol
Name
ID
Fabp2
fatty acid binding protein 2, intestinal
MGI:95478

Nomenclature History
STS D3Mit108
Synonyms Fabpi, Fabpi, I-FABP
Genetic Map
Chromosome 3
55.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 7)

Sequence Map
Chr3:122598310-122602421 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Fabp2 ± 2 cM)
Protein SuperFamily: lipid binding protein, FABP type
TreeFam: TF316894
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000023057 Ensembl Gene Model | MGI Sequence Detail 4112 C57BL/6J ± Kb
transcript NM_007980 RefSeq | MGI Sequence Detail 774 FVB/N
polypeptide P55050 UniProt | EBI | MGI Sequence Detail 132 Not Applicable
For the selected sequences
All sequences(15)
Alleles
and
phenotypes 		All alleles(2) : Targeted, knock-out(1) Targeted, other(1)
Male mutant mice exhibit increased body weight, hyperinsulinemia, increased leptin levels on a high fat diet and have elevated circulating levels of triglycerides. Female mutant mice exhibit a decreased body weight on a high fat diet compared to controls.
Polymorphisms RFLP(1) SNPs within 2kb(25 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process transport
Component cytoplasm, intracellular part...
Function binding, lipid binding...
External Resources: FuncBase
Expression Literature Summary: (15 records)
Data Summary: Assays (5)    Results (57)    Tissues (54)    Images (3)
Theiler Stages: 11,13,15,21,23,25,28
  Assay Type Assays   Results
      RT-PCR 5   57
cDNA source data(64)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(70) Genomic(1) cDNA(66) Primer pair(3)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000023057
DoTS DT.536663
Consensus CDS Project CCDS17813.1
UniGene 28398
DFCI TC1578192
NIA Mouse Gene Index U003809
Entrez Gene 14079
International Mouse Knockout Project Status Fabp2
Protein
domains
InterPro ID Description
IPR000463 Cytosolic fatty-acid binding
IPR000566 Lipocalin/cytosolic fatty-acid binding protein
IPR011038 Calycin-like
IPR012674 Calycin
Graphical View of Protein Domain Structure
References
(Earliest) J:7317 Alpers DH et al., "Cloning of a cDNA encoding rat intestinal fatty acid binding protein." Proc Natl Acad Sci U S A 1984 Jan;81(2):313-7
(Latest) J:151206 Babeu JP et al., "Hepatocyte nuclear factor 4alpha contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation." Am J Physiol Gastrointest Liver Physiol 2009 Jul;297(1):G124-34
All references(33)
Other
accession IDs 		MGD-MRK-9705
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory