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Mgat5 Gene Detail
 Symbol
Name
ID
Mgat5
mannoside acetylglucosaminyltransferase 5
MGI:894701

Nomenclature History
Synonyms 4930471A21Rik, 5330407H02Rik, beta1,6N-acetylglucosaminyltransferase V, GlcNAc-TV
Genetic Map
Chromosome 1
Syntenic
 
Mapping data( 2)
Sequence Map
Chr1:129101563-129379549 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase V
TreeFam: TF313714
Sequences
Representative Sequences Length Strain/Species Flank
genomic 107895 NCBI Gene Model | MGI Sequence Detail 277987 C57BL/6J ± Kb
transcript NM_145128 RefSeq | MGI Sequence Detail 3104 C57BL/6
polypeptide Q8R4G6 UniProt | EBI | MGI Sequence Detail 740 Not Applicable
For the selected sequences
All sequences(31)
Alleles
and
phenotypes 		All alleles(15) : Targeted, other(1) Gene trapped(14)
Mice homozygous for deficiencies in this gene have immune system abnormalities and reduced cancer growth and metastasis.
Polymorphisms SNPs within 2kb(1270 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(8)
Process protein amino acid N-linked glycosylation
Component Golgi apparatus, integral to membrane...
Function acetylglucosaminyltransferase activity, alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase activity...
External Resources: MouseFunc
Expression Literature Summary: (2 records)
cDNA source data(9)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents 		All nucleic(9) cDNA(9)
Microarray probesets(2)
Other database
links
EC 2.4.1.155
Ensembl Gene Model ENSMUSG00000036155
DoTS DT.101276315, DT.101722354, DT.91384886, DT.97392090
DFCI TC1585888, TC1598929, TC1667365
NIA Mouse Gene Index U000746, U236734
Entrez Gene 107895
International Mouse Knockout Project Status Mgat5
References
(Earliest) J:41554 Shoreibah M et al., "Isolation, characterization, and expression of a cDNA encoding N-acetylglucosaminyltransferase V." J Biol Chem 1993 25;268(21):15381-5
(Latest) J:147477 Soleimani L et al., "Beta N-acetylglucosaminyltransferase V (Mgat5) deficiency reduces the depression-like phenotype in mice." Genes Brain Behav 2008 Apr;7(3):334-43
All references(18)
Other
accession IDs 		MGI:1923060, MGI:2138276, MGI:2444778
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/20/2009
MGI_4.31
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