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Agrp Gene Detail
 Symbol
Name
ID
Agrp
agouti related protein
MGI:892013

Nomenclature History
Synonyms Agrt, Art
Genetic Map
Chromosome 8
cytoband D1-D2
 
Mapping data( 3)
Sequence Map
Chr8:108090600-108092198 bp, - strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: agouti-signaling protein/agouti-related protein
TreeFam: TF330729
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000005705 Ensembl Gene Model | MGI Sequence Detail 1599 C57BL/6J ± Kb
transcript NM_007427 RefSeq | MGI Sequence Detail 685 C57BL/6
polypeptide P56473 UniProt | EBI | MGI Sequence Detail 131 Not Applicable
For the selected sequences
All sequences(19)
Alleles
and
phenotypes 		All alleles(26) : Targeted, knock-out(2) Targeted, other(4) Gene trapped(20)
Mice homozygous for a null mutation do not exhibit any detectable abnormalities.
Polymorphisms SNPs within 2kb(15 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process adult feeding behavior, hormone-mediated signaling pathway...
Component extracellular region
Function neuropeptide hormone activity
External Resources: FuncBase
Expression Literature Summary: (3 records)
Data Summary: Assays (1)    Results (10)    Tissues (8)
Theiler Stages: 28
  Assay Type Assays   Results
      RT-PCR 1   10
cDNA source data(4)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(6) Genomic(1) cDNA(4) Primer pair(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000005705
DoTS DT.101724396, DT.102540030, DT.110848239
Consensus CDS Project CCDS22605.1
DFCI TC1589392, TC1661866
Entrez Gene 11604
International Mouse Knockout Project Status Agrp
Protein
domains
InterPro ID Description
IPR007733 Agouti
Graphical View of Protein Domain Structure
References
(Earliest) J:39234 Shutter JR et al., "Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice." Genes Dev 1997 Mar 1;11(5):593-602
(Latest) J:151087 Navarro M et al., "Deletion of agouti-related protein blunts ethanol self-administration and binge-like drinking in mice." Genes Brain Behav 2009 Jun;8(4):450-8
All references(35)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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