Symbol
Name
ID
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Synonyms
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2010010M04Rik, alpha E catenin, alpha(E)-catenin, Catna1
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Genetic Map
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Sequence Map
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Mammalian homology
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Sequences
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All sequences(35)
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Alleles and phenotypes
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All alleles(133) :
Targeted, other(1)
Gene trapped(131)
Spontaneous(1)
| Homozygous mutation of this gene results in embryonic lethality at the blastocyst stage. A conditional knockout in surface epithelium results in defects in hair follicle development and epidermal morphogenesis. |
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Polymorphisms
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RFLP(1)
SNPs within 2kb(357 from dbSNP Build 128)
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Gene Ontology (GO) classifications
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Expression
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Literature Summary: (31 records)
Data Summary:
Assays (6)
Results (119)
Tissues (111)
Images (30)
Theiler Stages: 3,4,5,20,22,24,25,26,28
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Assay Type |
Assays |
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Results |
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Western blot |
1 |
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1 |
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RNA in situ |
1 |
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93 |
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Immunohistochemistry |
4 |
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25 |
cDNA source data(454)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
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Molecular reagents
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All nucleic(459)
cDNA(458)
Primer pair(1)
Antibodies(4)
Microarray probesets(2)
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Other database links
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Protein domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:37373
Ozawa M et al.,
"The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species."
EMBO J 1989 Jun;8(6):1711-7
(Latest)
J:153566
Fujimura N et al.,
"Spatial and temporal regulation of Wnt/beta-catenin signaling is essential for development of the retinal pigment epithelium."
Dev Biol 2009 Oct 1;334(1):31-45
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All references(61)
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Other accession IDs
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MGD-MRK-1773, MGI:1913796, MGI:2147175, MGI:2147284
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