Symbol
Name
ID
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Synonyms
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CA II, CAII, Car-2, Ltw-5, Lvtw-5
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(31)
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Alleles
and
phenotypes
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All alleles(2) :
Targeted, knock-out(1)
Chemically induced(1)
| Homozygous mutant mice are growth retarded, display renal tubular acidosis, but mutants have not been recovered that display osteopetrosis as found in human CA-II deficiency. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
Phenotype Images (1)
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Polymorphisms
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RFLP(3)
SNPs within 2kb(156 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (14 records)
Data Summary:
Assays (7)
Results (120)
Tissues (110)
Images (42)
Theiler Stages: 15,17,19,20,22,24,26,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
1 |
|
3 |
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RNA in situ |
4 |
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115 |
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Immunohistochemistry |
2 |
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2 |
cDNA source data(240)
External Resources:
Allen Brain Atlas
GEO
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Molecular
reagents
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All nucleic(249)
Genomic(5)
cDNA(241)
Primer pair(2)
Other(1)
Antibodies(1)
Microarray probesets(2)
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Other database
links
|
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Protein
domains
|
| InterPro ID |
Description |
| IPR001148 |
Carbonic anhydrase, alpha-class, catalytic domain |
| IPR018338 |
Carbonic anhydrase, alpha-class, conserved site |
| IPR018440 |
Carbonic anhydrase, CA-II |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:5671
Davisson MT et al.,
"Genes on chromosome 3 of the mouse."
J Hered 1976 May-Jun;67(3):155-6
(Latest)
J:152014
Sjoblom M et al.,
"Duodenal acidity 'sensing' but not epithelial HCO3- supply is critically dependent on carbonic anhydrase II expression."
Proc Natl Acad Sci U S A 2009 Aug 4;106(31):13094-9
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All references(82)
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Other
accession IDs
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MGD-MRK-11922, MGD-MRK-11945, MGD-MRK-1760, MGD-MRK-1763, MGI:2139632
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