Symbol
Name
ID
|
|
|
Synonyms
|
5930429P18Rik, Ca2+/calmodulin-dependent protein kinase II, CaMK II, Camkg
|
|
Genetic Map
|
|
Chromosome 14
|
Syntenic
|
|
|
|
Mapping data(
2)
|
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(42)
|
Alleles
and
phenotypes
|
All alleles(3) :
Targeted, knock-out(1)
Targeted, other(1)
Gene trapped(1)
| Mice homozygous for a knock-out allele exhibit female infertility and decreased sensitivity of macrophages to ER stress-induced apoptosis. |
|
|
Polymorphisms
|
SNPs within 2kb(122 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (5 records)
Data Summary:
Assays (1)
Results (94)
Tissues (94)
Images (18)
Theiler Stages: 22
| |
Assay Type |
Assays |
|
Results |
| |
RNA in situ |
1 |
|
94 |
cDNA source data(14)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(16)
Genomic(1)
cDNA(14)
Primer pair(1)
Antibodies(1)
Microarray probesets(1)
|
Other database
links
|
| EC |
2.7.11.17 |
| Ensembl Gene Model |
ENSMUSG00000021820 |
| DoTS |
DT.101143928, DT.101337254, DT.101390072, DT.532494, DT.532555, DT.94275780 |
| Consensus CDS Project |
CCDS26855.1, CCDS26856.1, CCDS26857.1 |
| DFCI |
TC1572807, TC1589823, TC1592070, TC1640503, TC1729474 |
| NIA Mouse Gene Index |
U035289 |
| Entrez Gene |
12325 |
| International Mouse Knockout Project Status |
Camk2g |
|
Protein
domains
|
| InterPro ID |
Description |
| IPR000719 |
Protein kinase, catalytic domain |
| IPR002290 |
Serine/threonine-protein kinase domain |
| IPR008271 |
Serine/threonine-protein kinase, active site |
| IPR011009 |
Protein kinase-like domain |
| IPR013543 |
Calcium/calmodulin-dependent protein kinase II, association-domain |
| IPR015742 |
Calcium/calmodulin-dependent protein kinase II isoform |
| IPR017441 |
Protein kinase, ATP binding site |
| IPR017442 |
Serine/threonine-protein kinase-like domain |
| IPR020636 |
Calcium/calmodulin-dependent protein kinase-like |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:16757
Li X et al.,
"Localization of the CAMKG gene encoding gamma isoforms of multifunctional calcium/calmodulin-dependent protein kinase (CaM kinase) to human chromosome 10 band q22 and mouse chromosome 14."
Cytogenet Cell Genet 1994;66(2):113-6
(Latest)
J:154647
Timmins JM et al.,
"Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways."
J Clin Invest 2009 Oct;119(10):2925-41
|
All references(18)
|
Other
accession IDs
|
MGD-MRK-1746, MGI:2442091
|
Analysis Tools
MGI BioMart