Symbol
Name
ID
|
|
|
Synonyms
|
422/aP2, ALBP/Ap2, Ap2, Lbpl
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(29)
|
Alleles
and
phenotypes
|
All alleles(1) :
Targeted, knock-out(1)
| Homozygotes for a targeted null mutation exhibit susceptibility to diet-induced obesity, attenuated dibutyryl cAMP-induced adipocyte release of glycerol and free fatty acid, and reduced acute insulin secretion in response to beta-adrenergic stimulation. |
|
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Polymorphisms
|
All PCR and RFLP(7) :
PCR(5)
RFLP(2)
SNPs within 2kb(114 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (13 records)
Data Summary:
Assays (9)
Results (34)
Tissues (10)
Images (7)
Theiler Stages: 20,21,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
4 |
|
9 |
| |
Northern blot |
5 |
|
25 |
cDNA source data(236)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(254)
Genomic(8)
cDNA(239)
Primer pair(6)
Other(1)
Microarray probesets(4)
|
Other database
links
|
| Ensembl Gene Model |
ENSMUSG00000062515 |
| DoTS |
DT.537572, DT.94383239 |
| UniGene |
582 |
| PDB |
1A18, 1A2D, 1AB0, 1ACD, 1ADL, 1ALB, 1G74, 1G7N, 1LIB, 1LIC, 1LID, 1LIE, 1LIF, 2ANS, 2Q9S, 2QM9, 3HK1 |
| DFCI |
TC1572806, TC1587108 |
| NIA Mouse Gene Index |
U023829 |
| Entrez Gene |
11770 |
| International Mouse Knockout Project Status |
Fabp4 |
|
Protein
domains
|
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:7568
Bernlohr DA et al.,
"Expression of specific mRNAs during adipose differentiation: identification of an mRNA encoding a homologue of myelin P2 protein."
Proc Natl Acad Sci U S A 1984 Sep;81(17):5468-72
(Latest)
J:145453
Cao H et al.,
"Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism."
Cell 2008 Sep 19;134(6):933-44
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All references(50)
|
Other
accession IDs
|
MGD-MRK-1345, MGD-MRK-36068, MGI:107500
|
