Symbol
Name
ID
|
|
|
Synonyms
|
Akt, PKB, PKB/Akt, PKBalpha
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(35)
|
Alleles
and
phenotypes
|
All alleles(7) :
Targeted, knock-out(2)
Targeted, other(2)
Gene trapped(3)
| Mutant homozygotes are smaller than sibs due to retarded prenatal and postnatal growth and exhibit increased apopotosis and decreased lifespan with genotoxic stress. Mice are fertile, but males have attenuated spermatogenesis and abnormal testes. |
Phenotype Images (3)
|
|
Polymorphisms
|
RFLP(1)
SNPs within 2kb(106 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (82 records)
Data Summary:
Assays (9)
Results (146)
Tissues (63)
Images (6)
Theiler Stages: 19,20,21,22,23,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
Western blot |
5 |
|
46 |
| |
RT-PCR |
2 |
|
92 |
| |
Immunohistochemistry |
2 |
|
8 |
cDNA source data(214)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(219)
Genomic(2)
cDNA(214)
Primer pair(2)
Other(1)
Antibodies(6)
Microarray probesets(3)
|
Other database
links
|
|
Protein
domains
|
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:455
Cho M et al.,
"A linkage map of distal mouse chromosome 12."
Mamm Genome 1991;1(1):30-6
(Latest)
J:153804
Vijayaraj P et al.,
"Keratins regulate protein biosynthesis through localization of GLUT1 and -3 upstream of AMP kinase and Raptor."
J Cell Biol 2009 Oct 19;187(2):175-84
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All references(260)
|
Other
accession IDs
|
MGD-MRK-1257
|
