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Adssl1 Gene Detail
 Symbol
Name
ID
Adssl1
adenylosuccinate synthetase like 1
MGI:87947


Nomenclature History
Synonyms Adss
Genetic Map
Chromosome 12
Syntenic
 
Mapping data( 1)
Sequence Map
Chr12:113858300-113879551 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic    (Mammalian Orthology)
Protein SuperFamily: adenylosuccinate synthase
TreeFam: TF300486
Sequences
Representative Sequences Length Strain/Species Flank
genomic 11565 NCBI Gene Model | MGI Sequence Detail 21252 C57BL/6J ± Kb
transcript NM_007421 RefSeq | MGI Sequence Detail 1806 C57BL/6
polypeptide P28650 UniProt | EBI | MGI Sequence Detail 457 Not Applicable
For the selected sequences
All sequences(20)
Alleles
and
phenotypes
All alleles(1) : Gene trapped(1)
Polymorphisms SNPs within 2kb(176 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(14)
Process purine nucleotide biosynthetic process, purine nucleotide metabolic process...
Component cytoplasm, membrane...
Function adenylosuccinate synthase activity, GTP binding...
This is a GO Consortium Reference Genome Project gene.
External Resources: MouseFunc
Expression Literature Summary: (3 records)
Data Summary: Assays (4)    Results (34)    Tissues (28)    Images (7)
Theiler Stages: 15,17,21,23,24,28
  Assay Type Assays   Results
      RT-PCR 1   2
      RNA in situ 1   18
      Northern blot 1   5
      RNase protection 1   9
cDNA source data(29)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(35) Genomic(5) cDNA(29) Primer pair(1)
Microarray probesets(2)
Pathways
salvage pathways of purine nucleosides I
Other database
links
EC 6.3.4.4
Ensembl Gene Model ENSMUSG00000011148
DoTS DT.536543, DT.91297856
UniGene 3440
PDB 1IWE, 1J4B, 1LNY, 1LON, 1LOO, 1MEZ, 1MF0, 1MF1, 2DGN
DFCI TC1579255, TC1595695
NIA Mouse Gene Index U014451
Entrez Gene 11565
International Mouse Knockout Project Status Adssl1
Protein
domains
InterPro ID Description
IPR001114 Adenylosuccinate synthetase
IPR018220 Adenylosuccinate synthase, active site
Graphical View of Protein Domain Structure
References
(Earliest) J:11538 Guicherit OM et al., "Molecular cloning and expression of a mouse muscle cDNA encoding adenylosuccinate synthetase." J Biol Chem 1991 Nov 25;266(33):22582-7
(Latest) J:127524 Davie JK et al., "Target gene selectivity of the myogenic basic helix-loop-helix transcription factor myogenin in embryonic muscle." Dev Biol 2007 Nov 15;311(2):650-64
All references(9)
Other
accession IDs
MGD-MRK-1163, MGD-MRK-1164, MGI:2144855

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory