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MGI Accession ID: MGI:61716
J Number: J:13529
Title: Linkage of Mo and GS
Authors: Grahn D
Journal: Mouse News Lett
Volume: 47
Issue:
Date: 1972
Year: 1972
Pages: 20
Review Status: Unreviewed

Abstract:

Full text of MNL contribution: Linkage data: Gs - Mobr. In the course of several studies involving these mutants, we have derived what could be considered "most reliable" estimates of the Gs - Mo recombination frequency. This estimate can be biased by classification difficulties and non-random early mortality. In the particular outcrosses involved, Gs and Mobr are in repulsion. The reliable data from daughters use the + Mobr/++ and Gs Mobr/++ progeny and give a recombination frequency of 4.7 +/- 0.5% in 1665 offspring. For the males, the Gs/Y and +/Y progeny are most reliable. The recombination is 4.8 +/- 0.5% in 1756 offspring. The totals: 162 recombinants in 3421 progeny; 4.74 +/- 0.36%. It should be noted that the value can be as low as 2.5% without due regard for differential mortality and classification errors. Mobr-Blo. We have completed this allelic test (see MNL 44) and have observed no recombinants in 1222 classified offspring. This gives an upper limit (P=.05) of 0.5% for the recombination.

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